Chemical formula: C₁₄H₁₉NO₂ Molecular mass: 233.306 g/mol PubChem compound: 4158
Methylphenidate HCl is a mild central nervous system (CNS) stimulant. The mode of therapeutic action in Attention Deficit Hyperactivity Disorder (ADHD) is not known. Methylphenidate is thought to block the reuptake of noradrenaline and dopamine into the presynaptic neurone and increase the release of these monoamines into the extraneuronal space.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06BA04 | Methylphenidate | N Nervous system → N06 Psychoanaleptics → N06B Psychostimulants, agents used for ADHD and nootropics → N06BA Centrally acting sympathomimetics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| RITALIN Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| MATORIDE XR Prolonged-release tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| CONCERTA Extended-release tablet | Medicines and Medical Devices Safety Authority (NZ) | MPI, EU: SmPC |
Methylphenidate is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)Brazil (BR)Canada (CA)Cyprus (CY)
Ecuador (EC)Estonia (EE)Finland (FI)France (FR)Germany (DE)Hong Kong (HK)Ireland (IE)Israel (IL)
Lithuania (LT)Malta (MT)Netherlands (NL)New Zealand (NZ)Nigeria (NG)
Poland (PL)Romania (RO)
Singapore (SG)South Africa (ZA)
Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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