Methylphenidate

Chemical formula: C₁₄H₁₉NO₂  Molecular mass: 233.306 g/mol  PubChem compound: 4158

Therapeutic indications

Methylphenidate is indicated for:

Attention deficit hyperactivity disorder

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Methylphenidate is indicated as part of a comprehensive treatment programme for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6 years of age and over when remedial measures alone prove insufficient.

Treatment must be initiated and supervised by a physician specialised in the treatment of ADHD such as an expert paediatrician or a child and adolescent psychiatrist.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Methylphenidate is contraindicated in the following cases:

Glaucoma

Glaucoma

Phaeochromocytoma

Phaeochromocytoma

Non-selective, irreversible monoamine oxidase (MAO) inhibitors

Non selective Monoamine Oxidase Inhibitors and additionally not Reversible inhibitors of monoamine oxidase A (RIMAs)

Hyperthyroidism, thyrotoxicosis

at least one of
Hyperthyroidism
Thyrotoxicosis

Severe depression, anorexic disorders, psychotic symptoms, personality disorder

at least one of
Severe depression
H/O: depression
Anorexia nervosa
H/O: anorexia nervosa
Suicidal intent
History of attempted suicide
Psychotic symptom present
Mood disorder
History of mood disorder
Schizophrenia
H/O: schizophrenia
Antisocial personality disorder

Severe and episodic bipolar disorder

at least one of
Bipolar type I disorder currently in full remission
H/O: manic depressive disorder

Cardiovascular disorders

Cardiovascular disorder

Cerebrovascular disorders

at least one of
Cerebrovascular disease
Cerebral aneurysm
Vasculitis
CVA - Cerebrovascular accident

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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