Methylprednisolone

Chemical formula: C₂₂H₃₀O₅  Molecular mass: 374.471 g/mol  PubChem compound: 6741

Active ingredient description

Methylprednisolone is a synthetic glucocorticoid and a methyl derivative of prednisolone. Methylprednisolone is a potent anti-inflammatory agent with the capacity to profoundly inhibit the immune system.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D07AA01 Methylprednisolone D Dermatologicals → D07 Corticosteroids, dermatological preparations → D07A Corticosteroids, plain → D07AA Corticosteroids, weak (group I)
Discover more medicines within D07AA01
D10AA02 Methylprednisolone D Dermatologicals → D10 Anti-acne preparations → D10A Anti-acne preparations for topical use → D10AA Corticosteroids, combinations for treatment of acne
Discover more medicines within D10AA02
H02AB04 Methylprednisolone H Systemic hormonal preparations, excl. Sex hormones and insulins → H02 Corticosteroids for systemic use → H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN → H02AB Glucocorticoids
Discover more medicines within H02AB04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MEDROL Tablet FDA, National Drug Code (US) MPI, US: SPL/Old
MEDRONE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
SOLU-MEDRONE Powder for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 2375-03-3
CAS Substance: 2921-57-5
CAS Substance: 53-36-1
CAS Substance: 83-43-2
DrugBank Drug: DB00959
KEGG Drug: D00407
PubChem Compound: 6741
RxNorm Ingredient: 6902
SNOMED-CT Concept: 116593003
Methylprednisolone (substance)
UNII Identifier: X4W7ZR7023
METHYLPREDNISOLONE

Medicines

Methylprednisolone is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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