Miconazole

Chemical formula: C₁₈H₁₄Cl₄N₂O  Molecular mass: 416.129 g/mol  PubChem compound: 4189

Therapeutic indications

Miconazole is indicated for:

Candidosis of the oropharynx

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Oral treatment of candidosis of the oropharynx.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Vulvovaginal candidosis

Population group: women, only adults (18 years old or older)

For the local treatment of vulvovaginal candidosis and superinfections due to gram-positive bacteria.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Mycotic infections of the skin and nails

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

For the treatment of mycotic infections of the skin and nails and superinfections due to Gram-positive bacteria.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Candidosis of the oropharynx

Population group: only newborns (0 - 40 days old) , infants (40 days - 1 year old)

Oral treatment of candidosis of the oropharynx.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Miconazole is contraindicated in the following cases:

Hypersensitivity to miconazole

Miconazole allergy

Liver dysfunction

Hepatic insufficiency

Ergot alkaloids

at least one of
Ergot alkaloids
Ergot alkaloids
Ergot alkaloids

Triazolam, midazolam

at least one of
Triazolam
Midazolam

HMG-CoA reductase inhibitors that are subject to metabolism by CYP3A4

HMG CoA reductase inhibitors and additionally CYP3A4 substrates

Substrates known to prolong the QT-interval that are subject to metabolism by CYP3A4

Drugs prolonging QT interval and additionally CYP3A4 substrates

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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