Midazolam

Chemical formula: C₁₈H₁₃ClFN₃  Molecular mass: 325.767 g/mol  PubChem compound: 4192

Active ingredient description

Midazolam is a derivative of the imidazobenzodiazepine group. The free base is a lipophilic substance with low solubility in water. The basic nitrogen in position 2 of the imidazobenzodiazepine ring system enables the active ingredient of midazolam to form water-soluble salts with acids.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05CD08 Midazolam N Nervous system → N05 Psycholeptics → N05C Hypnotics and sedatives → N05CD Benzodiazepine derivatives
Discover more medicines within N05CD08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BUCCOLAM Oromucosal solution European Medicines Agency (EU) MPI, EU: SmPC
OZALIN Oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MIDAZOLAM Solution for injection or infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 59467-70-8
CAS Substance: 59467-96-8
DrugBank Drug: DB00683
KEGG Drug: D00550
PubChem Compound: 4192
RxNorm Ingredient: 6960
SNOMED-CT Concept: 373476007
Midazolam (substance)
UNII Identifier: R60L0SM5BC
MIDAZOLAM

Medicines

Midazolam is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Croatia (HR)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

  • DOMI as MIDAZOLAM HYDROCHLORIDE
  • DORMICUM as MIDAZOLAM HYDROCHLORIDE

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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