Chemical formula: C₅₉H₁₀₉N₆O₁₉P Molecular mass: 1,277.515 g/mol
Mifamurtide (MTP-PE) is a fully synthetic derivative of muramyl dipeptide (MDP). MTP-PE is a potent activator of monocytes and macrophages. The exact mechanism by which mifamurtide activation of monocytes and macrophages leads to anti-tumour activity in animals and humans is not yet known.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L03AX15 | Mifamurtide | L Antineoplastic and immunomodulating agents → L03 Immunostimulants → L03A Immunostimulants → L03AX Other immunostimulants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MEPACT Powder for concentrate for dispersion for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
Mifamurtide is an active ingredient of these brands:
Austria (AT)Brazil (BR)Croatia (HR)Cyprus (CY)Estonia (EE)Finland (FI)Ireland (IE)Israel (IL)Italy (IT)Lithuania (LT)Netherlands (NL)Poland (PL)Romania (RO)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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