Mifamurtide

Chemical formula: C₅₉H₁₀₉N₆O₁₉P  Molecular mass: 1,277.515 g/mol 

Therapeutic indications

Mifamurtide is indicated for:

Non-metastatic osteosarcoma

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Mifamurtide is indicated in children, adolescents and young adults for the treatment of high-grade resectable non-metastatic osteosarcoma after macroscopically complete surgical resection. It is used in combination with post-operative multi-agent chemotherapy. Safety and efficacy have been assessed in studies of patients 2 to 30 years of age at initial diagnosis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Mifamurtide is contraindicated in the following cases:

Calcineurin inhibitors

Calcineurin inhibitors

Non-steroidal-anti-inflammatory drugs

Non steroidal anti-inflammatory drugs (NSAIDS)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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