Morphine

Chemical formula: C₁₇H₁₉NO₃  Molecular mass: 285.338 g/mol  PubChem compound: 5288826

Active ingredient description

Morphine is a narcotic analgesic obtained from opium. Morphine acts as an agonist at opiate receptors in the CNS particularly Mu and to a lesser extent Kappa receptors. Mu receptors are thought to mediate supraspinal analgesia, respiratory depression and euphoria, and Kappa receptors, spinal analgesia, miosis and sedation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02AA01 Morphine N Nervous system → N02 Analgesics → N02A Opioids → N02AA Natural opium alkaloids
Discover more medicines within N02AA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MORPHGESIC Controlled release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
KADIAN Capsule extended-release FDA, National Drug Code (US) MPI, US: SPL/PLR
MS CONTIN Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
MORPHINE SULFATE Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 64-31-3
DrugBank Drug: DB00295
KEGG Drug: D08233
PubChem Compound: 5288826
RxNorm Ingredient: 7052
SNOMED-CT Concept: 373529000
Morphine (substance)
UNII Identifier: 76I7G6D29C
MORPHINE

Medicines

Morphine is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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