Neostigmine Other names: Prostigmin Vagostigmin

Chemical formula: C₁₂H₁₉N₂O₂⁺  Molecular mass: 223.292 g/mol  PubChem compound: 4456

Therapeutic indications

Neostigmine is indicated for:

Myasthenia Gravis

Population group: only minors (0 - 18 years old) , adults (18 years old or older)

Myasthenia gravis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Paralytic ileus

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Paralytic ileus

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Antagonist to non-depolarizing neuromuscular blockade

Population group: only minors (0 - 18 years old) , adults (18 years old or older)

Reversal of neuromuscular blockade with neostigmine should not be attempted unless there is spontaneous recovery from paralysis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Post-operative urinary retention

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Postoperative retention of urine

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Paroxysmal supraventricular tachycardia

Population group: only adults (18 - 65 years old)

Treatment should be reserved for severe cases not responding to conventional treatment and under the close supervision of a specialist experienced with its use.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Neostigmine is contraindicated in the following cases:

Mechanical obstruction of gastrointestinal tract

Gastrointestinal obstruction

Mechanical obstruction of urinary tracts

Mechanical urinary obstruction

Peritonitis

Peritonitis

Doubtful bowel viability

BD - Bowel dysfunction

Depolarising muscle relaxants

Suxamethonium

Cyclopropane or halothane anaesthesia

at least one of
Halothane
CYCLOPROPANE

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

Summary of Product Characteristics (SPC) 2015: NEOSTIGMINE BROMIDE Tablet
Summary of Product Characteristics (SPC) 2021: NEOSTIGMINE Sterile injection
< Previous: Overview
Next: Precautions >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈