Norethisterone Other names: Norethindrone 19-nor-17α-ethynyltestosterone

Chemical formula: C₂₀H₂₆O₂  Molecular mass: 298.419 g/mol  PubChem compound: 6230

Active ingredient description

Norethisterone has progestational actions similar to those of progesterone, but is a more potent inhibitor of ovulation and has weak oestrogenic and androgenic properties. It is used to treat a number of disorders of the menstrual cycle.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G03AC01 Norethisterone G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03A Hormonal contraceptives for systemic use → G03AC Progestogens
Discover more medicines within G03AC01
G03DC02 Norethisterone G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03D Progestogens → G03DC Estren derivatives
Discover more medicines within G03DC02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PRIMOLUT N Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
JENCYCLA Tablet FDA, National Drug Code (US) MPI, US: SPL/Old
UTOVLAN Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 51-98-9
CAS Substance: 68-22-4
DrugBank Drug: DB00717
KEGG Drug: D00182
PubChem Compound: 6230
RxNorm Ingredient: 7514
SNOMED-CT Concept: 126102009
Norethisterone (substance)
UNII Identifier: T18F433X4S
NORETHINDRONE

Medicines

Norethisterone is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) ESTALIS as NORETHINDRONE ACETATE
  • (combination) KLIOGEST as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) SEQUIDOT as NORETHINDRONE ACETATE
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Brazil (BR)

Canada (CA)

Croatia (HR)

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) NOVOFEM as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Cyprus (CY)

  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Ecuador (EC)

  • PRIMOLUT NOR as NORETHINDRONE ACETATE

  • (combination) FEMGYL as NORETHINDRONE ENANTHATE
  • (combination) MESIGYNA as NORETHINDRONE ENANTHATE
  • (combination) MESQUIL as NORETHINDRONE ENANTHATE
  • (combination) MESYGEST as NORETHINDRONE ENANTHATE
  • (combination) NOFERTYL as NORETHINDRONE ENANTHATE
  • (combination) SOLUNA as NORETHINDRONE ENANTHATE

Estonia (EE)

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) EVIANA as NORETHINDRONE ACETATE
  • (combination) KLIANE
  • (combination) KLIOGEST as NORETHINDRONE ACETATE
  • (combination) NOVOFEM as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Finland (FI)

France (FR)

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) KLIOGEST as NORETHINDRONE ACETATE
  • (combination) NOVOFEMME as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Germany (DE)

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) CLIOVELLE as NORETHINDRONE ACETATE
  • (combination) ESTRAMON COMP as NORETHINDRONE ACETATE
  • (combination) KLIOGEST as NORETHINDRONE ACETATE
  • (combination) NOVOFEM as NORETHINDRONE ACETATE
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Hong Kong (HK)

Ireland (IE)

  • NORIDAY

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) EVOREL CONTI as NORETHINDRONE ACETATE
  • (combination) KLIOGEST as NORETHINDRONE ACETATE
  • (combination) NOVOFEM as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Israel (IL)

  • PRIMOLUT NOR as NORETHINDRONE ACETATE

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) EVIANA as NORETHINDRONE ACETATE
  • (combination) EVOREL CONTI as NORETHINDRONE ACETATE
  • (combination) NOVOFEM as NORETHINDRONE ACETATE

Italy (IT)

  • (combination) RYEQO as Norethisterone acetate

Japan (JP)

Lithuania (LT)

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) KLIANE
  • (combination) KLIOGEST as NORETHINDRONE ACETATE
  • (combination) NOVOFEM as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

  • PRIMOLUT NOR as NORETHINDRONE ACETATE

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) CLIOVELLE as NORETHINDRONE ACETATE
  • (combination) ESTALIS as NORETHINDRONE ACETATE
  • (combination) KLIOGEST as NORETHINDRONE ACETATE
  • (combination) NOVOFEM as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) SYSTEN CONTI as NORETHINDRONE ACETATE
  • (combination) SYSTEN SEQUI as NORETHINDRONE ACETATE
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Romania (RO)

  • (combination) RYEQO as Norethisterone acetate

Singapore (SG)

South Africa (ZA)

Spain (ES)

  • PRIMOLUT NOR as NORETHINDRONE ACETATE

  • (combination) ACTIVELLE as NORETHINDRONE ACETATE
  • (combination) DUOFEMME as NORETHINDRONE ACETATE
  • (combination) ESTALIS SEQUIDOT as Norethisterone acetate
  • (combination) EVIANA as NORETHINDRONE ACETATE
  • (combination) RYEQO as Norethisterone acetate
  • (combination) TRISEQUENS as NORETHINDRONE ACETATE

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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