Pentoxifylline

Chemical formula: C₁₃H₁₈N₄O₃  Molecular mass: 278.307 g/mol  PubChem compound: 4740

Active ingredient description

Pentoxifylline has been shown to increase leukocyte deformability and to inhibit neutrophil adhesion and activation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C04AD03 Pentoxifylline C Cardiovascular system → C04 Peripheral vasodilators → C04A Peripheral vasodilators → C04AD Purine derivatives
Discover more medicines within C04AD03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TRENTAL 400 Modified release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 6493-05-6
DrugBank Drug: DB00806
KEGG Drug: D00501
PubChem Compound: 4740
RxNorm Ingredient: 8013
SNOMED-CT Concept: 387522004
Pentoxifylline (substance)
UNII Identifier: SD6QCT3TSU
PENTOXIFYLLINE

Medicines

Pentoxifylline is an active ingredient of these brands:

Brazil (BR)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

Germany (DE)

Israel (IL)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Romania (RO)

Singapore (SG)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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