Chemical formula: C₁₃H₁₈N₄O₃ Molecular mass: 278.307 g/mol PubChem compound: 4740
Leukocyte properties of haemorrheologic importance have been modified in animal and in vitro human studies. Pentoxifylline has been shown to increase leukocyte deformability and to inhibit neutrophil adhesion and activation.
The half life of absorption of pentoxifylline is 4-6 hours. Pentoxifylline is extensively metabolised, mainly in the liver. Sixty percent of a single dose of pentoxifylline is eliminated via the kidney over 24 hours.
Nothing of clinical relevance.
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