Phenytoin Other names: Phenytoin sodium Diphenylhydantoin

Chemical formula: C₁₅H₁₂N₂O₂  Molecular mass: 252.268 g/mol  PubChem compound: 1775

Active ingredient description

Phenytoin is effective in various animal models of generalised convulsive disorders, reasonably effective in models of partial seizures but relatively ineffective in models of myoclonic seizures. It appears to stabilise rather than raise the seizure threshold and prevents spread of seizure activity rather than abolish the primary focus of seizure discharge.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N03AB02 Phenytoin N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AB Hydantoin derivatives
Discover more medicines within N03AB02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DILANTIN-125 Oral suspension FDA, National Drug Code (US) MPI, US: SPL/PLR
EPANUTIN Oral suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DILANTIN INFATABS Chewable tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
DILANTIN Extended-release capsule FDA, National Drug Code (US) MPI, US: SPL/PLR
EPANUTIN READY MIXED Solution for injection or infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 57-41-0
CAS Substance: 630-93-3
DrugBank Drug: DB00252
KEGG Drug: D00512
PubChem Compound: 1775
RxNorm Ingredient: 8183
SNOMED-CT Concept: 387220006
Phenytoin (substance)
UNII Identifier: 6158TKW0C5
PHENYTOIN

Medicines

Phenytoin is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Ecuador (EC)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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