Chemical formula: C₁₅H₁₂N₂O₂ Molecular mass: 252.268 g/mol PubChem compound: 1775
Phenytoin is effective in various animal models of generalised convulsive disorders, reasonably effective in models of partial seizures but relatively ineffective in models of myoclonic seizures. It appears to stabilise rather than raise the seizure threshold and prevents spread of seizure activity rather than abolish the primary focus of seizure discharge.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N03AB02 | Phenytoin | N Nervous system → N03 Antiepileptics → N03A Antiepileptics → N03AB Hydantoin derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DILANTIN Extended-release capsule | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| DILANTIN-125 Oral suspension | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| EPANUTIN READY MIXED Solution for injection or infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DILANTIN INFATABS Chewable tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| EPANUTIN Oral suspension | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Phenytoin is an active ingredient of these brands:
Australia (AU)Canada (CA)Ecuador (EC)Finland (FI)Germany (DE)
Hong Kong (HK)Ireland (IE)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)Poland (PL)
Romania (RO)
Singapore (SG)Tunisia (TN)Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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