Pravastatin Other names: Pravastatin sodium

Chemical formula: C₂₃H₃₆O₇  Molecular mass: 424.528 g/mol  PubChem compound: 54687

Therapeutic indications

Pravastatin is indicated for:

Primary prevention of cardiovascular disease

Population group: only adults (18 years old or older)

Reduction of cardiovascular mortality and morbidity in patients with a history of myocardial infarction or unstable angina pectoris and with either normal or increased cholesterol levels, as an adjunct to correction of other risk factors.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Primary hypercholesterolaemia, mixed dyslipidaemia

Population group: only adults (18 years old or older)

Treatment of primary hypercholesterolaemia or mixed dyslipidaemia, as an adjunct to diet, when response to diet and other non-pharmacological treatments (e.g. exercise, weight reduction) is inadequate.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Post transplantation hyperlipidaemia

Population group: only adults (18 years old or older)

Reduction of post transplantation hyperlipidaemia in-patient receiving immunosuppressive therapy following solid organ transplantation.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Secondary prevention of cardiovascular diseases

Population group: only adults (18 years old or older)

Reduction of cardiovascular mortality and morbidity in patients with a history of myocardial infarction or unstable angina pectoris and with either normal or increased cholesterol levels, as an adjunct to correction of other risk factors.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Heterozygous familial hypercholesterolaemia

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Children and adolescents (8-18 years of age) with heterozygous familial hypercholesterolaemia.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Pravastatin is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Fusidic acid

Fusidic acid

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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