Ribociclib

Chemical formula: C₂₃H₃₀N₈O  Molecular mass: 434.548 g/mol  PubChem compound: 44631912

Therapeutic indications

Ribociclib is indicated for:

Locally advanced or metastatic breast cancer with HR-positive, HER2-negative

Population group: only adults (18 years old or older)

Ribociclib is indicated for the treatment of women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer in combination with an aromatase inhibitor or fulvestrant as initial endocrine-based therapy, or in women who have received prior endocrine therapy.

In pre- or perimenopausal women, the endocrine therapy should be combined with a luteinising hormone-releasing hormone (LHRH) agonist.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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