Chemical formula: C₈H₅F₃N₂OS Molecular mass: 234.198 g/mol PubChem compound: 5070
Riluzole is proposed to act by inhibiting glutamate processes. The mode of action is unclear. It is suggested that glutamate (the primary excitatory neurotransmitter in the central nervous system) plays a role for cell death in the ALS disease.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N07XX02 | Riluzole | N Nervous system → N07 Other nervous system drugs → N07X Other nervous system drugs → N07XX Other nervous system drugs |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| RILUTEK Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Riluzole is an active ingredient of these brands:
Canada (CA)Croatia (HR)Cyprus (CY)Finland (FI)Ireland (IE)Israel (IL)Italy (IT)Japan (JP)Lithuania (LT)Mexico (MX)New Zealand (NZ)Romania (RO)Singapore (SG)South Africa (ZA)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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