Roxithromycin

Chemical formula: C₄₁H₇₆N₂O₁₅  Molecular mass: 837.047 g/mol  PubChem compound: 6915744

Active ingredient description

Roxithromycin is a semi-synthetic macrolide antibiotic. Roxithromycin is bacteriostatic at low concentrations and bactericidal at high concentrations. It binds to the 50S subunit of the 70S ribosome, thereby disrupting bacterial protein synthesis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01FA06 Roxithromycin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01F Macrolides, lincosamides and streptogramins → J01FA Macrolides
Discover more medicines within J01FA06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ARROW ROXITHROMYCIN Coated tablet Medicines and Medical Devices Safety Authority (NZ) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 80214-83-1
DrugBank Drug: DB00778
KEGG Drug: D01710
PubChem Compound: 6915744
RxNorm Ingredient: 9478
SNOMED-CT Concept: 96037004
Roxithromycin (substance)
UNII Identifier: 21KOF230FA
ROXITHROMYCIN

Medicines

Roxithromycin is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Cyprus (CY)

France (FR)

Germany (DE)

Israel (IL)

Japan (JP)

Malta (MT)

New Zealand (NZ)

Poland (PL)

Singapore (SG)

South Africa (ZA)

Tunisia (TN)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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