Sacituzumab govitecan

Chemical formula: C₇₆H₁₀₄N₁₂O₂₄S  Molecular mass: 1,600.701 g/mol 

Therapeutic indications

Sacituzumab govitecan is indicated for:

Triple-negative breast cancer (mTNBC)

Population group: only adults (18 years old or older)

Sacituzumab govitecan as monotherapy is indicated for the treatment of adult patients with unresectable or metastatic triple-negative breast cancer (mTNBC) who have received two or more prior systemic therapies, including at least one of them for advanced disease.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hormone receptor (HR)-positive, HER2-negative breast cancer

Population group: only adults (18 years old or older)

Trodelvy as monotherapy is indicated for the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, HER2-negative breast cancer who have received endocrine-based therapy, and at least two additional systemic therapies in the advanced setting.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Sacituzumab govitecan is contraindicated in the following cases:

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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