Saquinavir

Chemical formula: C₃₈H₅₀N₆O₅  Molecular mass: 670.841 g/mol  PubChem compound: 441243

Active ingredient description

Saquinavir selectively inhibits the HIV protease, thereby preventing the creation of mature infectious virus particles. The HIV protease is an essential viral enzyme required for the specific cleavage of viral gag and gag-pol polyproteins.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J05AE01 Saquinavir J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AE Protease inhibitors
Discover more medicines within J05AE01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
INVIRASE Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 127779-20-8
CAS Substance: 149845-06-7
DrugBank Drug: DB01232
KEGG Drug: D00429
PubChem Compound: 441243
RxNorm Ingredient: 83395
SNOMED-CT Concept: 372530001
Saquinavir (substance)
UNII Identifier: L3JE09KZ2F
SAQUINAVIR

Medicines

Saquinavir is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Cyprus (CY)

Estonia (EE)

Hong Kong (HK)

Ireland (IE)

Lithuania (LT)

Netherlands (NL)

Poland (PL)

South Africa (ZA)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.