Sotalol

Chemical formula: C₁₂H₂₀N₂O₃S  Molecular mass: 272.364 g/mol  PubChem compound: 5253

Active ingredient description

D,l-sotalol is a non-selective hydrophilic β-adrenergic receptor blocking agent, devoid of intrinsic sympathomimetic activity or membrane stabilizing activity. Sotalol has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C07AA07 Sotalol C Cardiovascular system → C07 Beta blocking agents → C07A Beta blocking agents → C07AA Beta blocking agents, non-selective
Discover more medicines within C07AA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SOTALOL Tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 3930-20-9
CAS Substance: 959-24-0
DrugBank Drug: DB00489
PubChem Compound: 5253
RxNorm Ingredient: 9947
SNOMED-CT Concept: 372911006
Sotalol (substance)
UNII Identifier: A6D97U294I
SOTALOL

Medicines

Sotalol is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Croatia (HR)

  • DAROB as SOTALOL HYDROCHLORIDE

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Ireland (IE)

Italy (IT)

Japan (JP)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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