Sotalol

Chemical formula: C₁₂H₂₀N₂O₃S  Molecular mass: 272.364 g/mol  PubChem compound: 5253

Therapeutic indications

Sotalol is indicated for:

Ventricular tachyarrhythmia

Population group: only adults (18 years old or older)

Ventricular arrhythmias:

  • Treatment of life-threatening ventricular tachyarrhythmias;
  • Treatment of symptomatic non-sustained ventricular tachyarrhythmias.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of paroxysmal atrial tachycardia

Population group: only adults (18 years old or older)

Preventive procedure and additionally Atrial paroxysmal tachycardia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of paroxysmal atrial fibrillation

Population group: only adults (18 years old or older)

Preventive procedure and additionally AF - Paroxysmal atrial fibrillation

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of paroxysmal A-V nodal re-entrant tachycardia

Population group: only adults (18 years old or older)

Preventive procedure and additionally Re-entrant atrioventricular node tachycardia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of paroxysmal A-V re-entrant tachycardia using accessory pathways

Population group: only adults (18 years old or older)

Preventive procedure and additionally Re-entrant atrial tachycardia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of paroxysmal supraventricular tachycardia after cardiac surgery

Population group: only adults (18 years old or older)

Preventive procedure and additionally
Paroxysmal supraventricular tachycardia and additionally Operative procedure on heart

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Maintenance of normal sinus rhythm following conversion of atrial fibrillation or atrial flutter

Population group: only adults (18 years old or older)

Direct current atrial defibrillation

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Sotalol is contraindicated in the following cases:

Sick sinus syndrome

Sick sinus syndrome

Second degree AV heart block

Second degree atrioventricular block

Third degree AV heart block

Complete atrioventricular block

Long QT syndrome

at least one of
Prolonged QT interval
Long QT syndrome

Torsades de pointes

Torsades de pointes

Symptomatic sinus bradycardia

Symptomatic sinus bradycardia

Congestive heart failure

Congestive heart failure

Cardiogenic shock

Cardiogenic shock

Anaesthesia and myocardial depression

General anesthesia and additionally Myocardial dysfunction

Pheochromocytoma

Phaeochromocytoma

Hypotension

Hypotension

Raynaud's phenomenon

Raynaud's phenomenon

Peripheral arterial occlusive disease

Peripheral arterial occlusive disease

Chronic obstructive airway disease

at least one of
Chronic obstructive lung disease
History of chronic obstructive airway disease

Bronchial asthma

at least one of
Airway hyperreactivity
H/O: asthma

Metabolic acidosis

Metabolic acidosis

Renal failure (creatinine clearance <10 ml/min)

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Related medicines

Summary of Product Characteristics (SPC) 2019: SOTALOL Tablets
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