Chemical formula: C₂₀H₂₈N₂O₅S Molecular mass: 408.512 g/mol PubChem compound: 129211
Tamsulosin binds selectively and competitively to post-synaptic α1-adrenoreceptors, prevailingly their subtypes designated α1A and α1D. Thus relaxation of smooth muscles of the prostate and urethra is achieved, which leads to a reduction of tonus and an improvement of the urinary flow.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G04CA02 | Tamsulosin | G Genito urinary system and sex hormones → G04 Urologicals → G04C Drugs used in benign prostatic hypertrophy → G04CA Alpha-adrenoreceptor antagonists |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| OMSULA Prolonged-release capsule, hard | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| FLOMAX Capsule | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Tamsulosin is an active ingredient of these brands:
Austria (AT)
Brazil (BR)Croatia (HR)
Ecuador (EC)
Estonia (EE)Finland (FI)Germany (DE)Ireland (IE)Israel (IL)
Japan (JP)Lithuania (LT)Malta (MT)Nigeria (NG)
Poland (PL)
Romania (RO)South Africa (ZA)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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