Tapentadol

Chemical formula: C₁₄H₂₃NO  Molecular mass: 221.339 g/mol  PubChem compound: 9838022

Active ingredient description

Tapentadol is a strong analgesic with µ-agonistic opioid and additional noradrenaline reuptake inhibition properties. Tapentadol exerts its analgesic effects directly without a pharmacologically active metabolite.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
N02AX06 N Nervous system → N02 Analgesics → N02A Opioids → N02AX Other opioids
Discover more medicines within N02AX06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 PALEXIA SR Prolonged-release tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 NUCYNTA ER Film-coated tablet MPI, US: SPL/PLR FDA, National Drug Code (US)
 PALEXIA Oral solution MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 PALEXIA Film-coated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 175591-23-8
DrugBank Drug: DB06204
KEGG Drug: D06007
PubChem Compound: 9838022
RxNorm Ingredient: 787390
SNOMED-CT Concept: 441757005
Tapentadol (substance)
UNII Identifier: H8A007M585
TAPENTADOL

Medicines

Tapentadol is an active ingredient of these brands:

Australia (AU)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Austria (AT)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Brazil (BR)

  • PALEXIS as TAPENTADOL HYDROCHLORIDE

Canada (CA)

  • NUCYNTA as TAPENTADOL HYDROCHLORIDE

Croatia (HR)

Cyprus (CY)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Ecuador (EC)

  • PALEXIS as TAPENTADOL HYDROCHLORIDE

Estonia (EE)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Ireland (IE)

  • APENETA as Tapentadol maleate hemihydrate
  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Lithuania (LT)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Malta (MT)

Mexico (MX)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Netherlands (NL)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Poland (PL)

  • ADOBEN as TAPENTADOL MALEATE HEMIHYDRATE
  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Singapore (SG)

  • NUCYNTA as TAPENTADOL HYDROCHLORIDE

South Africa (ZA)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE

Spain (ES)

  • PALEXIA as TAPENTADOL HYDROCHLORIDE
  • YANTIL as TAPENTADOL HYDROCHLORIDE

United Kingdom (UK)

United States (US)

  • NUCYNTA as TAPENTADOL HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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