Tedizolid

Chemical formula: C₁₇H₁₅FN₆O₃  Molecular mass: 370.344 g/mol 

Active ingredient description

Tedizolid is an oxazolidinone prodrug. The antibacterial activity of tedizolid is mediated by binding to the 50S subunit of the bacterial ribosome resulting in inhibition of protein synthesis. Tedizolid is primarily active against Gram-positive bacteria.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01XX11 J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01X Other antibacterials → J01XX Other antibacterials
Discover more medicines within J01XX11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SIVEXTRO Powder for concentrate for solution for infusion European Medicines Agency (EU) MPI, EU: SmPC
SIVEXTRO Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 856866-72-3
DrugBank Drug: DB14569
KEGG Drug: D09685
RxNorm Ingredient: 1540825
SNOMED-CT Concept: 703912007
Tedizolid (substance)
UNII Identifier: 97HLQ82NGL
TEDIZOLID

Medicines

Tedizolid is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Poland (PL)

Singapore (SG)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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