Thiopental Other names: Sodium thiopental Sodium pentothal Thiopentone sodium Trapanal

Chemical formula: C₁₁H₁₇N₂NaO₂S  Molecular mass: 242.338 g/mol  PubChem compound: 3000715

Interactions

Thiopental interacts in the following cases:

Interaction

Antithrombotic agents

Interaction

at least one of
Opioids
Psycholeptics

Pregnancy

It has been shown that thiopental can be used without adverse effects during pregnancy. However, when considering use of thiopental the clinician should only use the drug when the expected benefits outweigh any potential risks.

Nursing mothers

Thiopental readily crosses the placental barrier and also appears in breast milk. Animal reproduction studies have not been conducted with thiopental. Therefore, breast-feeding should be temporarily suspended (for at least 12 hours) or breast milk expressed before the induction of anaesthesia.

Carcinogenesis, mutagenesis and fertility

Fertility

There are no data on the effect of thiopental on human fertility.

Effects on ability to drive and use machines

This medicinal product has major influence on the ability to drive and use machines. Even though the recovery after use of this medicinal product is rapid; post-operative vertigo, disorientation and sedation may be prolonged and out-patients given thiopental should therefore be advised not to drive or use machinery especially within the first 24 to 36 hours.

Cross-check medications

Review your medication to ensure that there are no potentially harmful drug interactions or contraindications.

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