Thiopental Other names: Sodium thiopental Sodium pentothal Thiopentone sodium Trapanal

Chemical formula: C₁₁H₁₇N₂NaO₂S  Molecular mass: 242.338 g/mol  PubChem compound: 3000715

Therapeutic indications

Thiopental is indicated for:

Indication

Population group: only adults (18 years old or older)

at least one of
Tetany
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
Generalized idiopathic epilepsy and epileptic syndromes
Other generalized epilepsy and epileptic syndromes
Epilepsy, unspecified
Complex partial status epilepticus
Eclampsia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Indication

Population group: only adults (18 years old or older)

Maintenance of general anaesthesia

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Thiopental is contraindicated in the following cases:

Contraindication

at least one of
Disorders of porphyrin and bilirubin metabolism
Shock, not elsewhere classified
Cardiac failure
Status asthmaticus
Totally obstructed airway
Chronic constrictive pericarditis
Multiple valve diseases
Rheumatic mitral valve diseases
Rheumatic aortic valve diseases
Rheumatic tricuspid valve diseases
Nonrheumatic mitral valve disorders
Nonrheumatic aortic valve disorders
Mitral valve disorders in diseases classified elsewhere
Aortic valve disorders in diseases classified elsewhere
Tricuspid valve disorders in diseases classified elsewhere
Pulmonary valve disorders in diseases classified elsewhere
Multiple valve disorders in diseases classified elsewhere
Congenital malformations of aortic and mitral valves
Stenosis of aorta
Chronic renal failure
Unspecified renal failure
Other chronic obstructive pulmonary disease
Myasthenia gravis and other myoneural disorders
Myxoedema coma
Hypothyroidism, unspecified
Primary adrenocortical insufficiency
Drug-induced adrenocortical insufficiency
Other and unspecified adrenocortical insufficiency

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Summary of Product Characteristics (SPC) 2018: THIOPENTAL Powder for solution for injection
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