Tislelizumab

Therapeutic indications

Tislelizumab is indicated for:

Oesophageal squamous cell carcinoma

Population group: only adults (18 years old or older)

Tislelizumab as monotherapy is indicated for the treatment of adult patients with unresectable, locally advanced or metastatic oesophageal squamous cell carcinoma after prior platinum-based chemotherapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Non-small cell lung cancer

Population group: only adults (18 years old or older)

Tislelizumab as monotherapy is indicated for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer after prior platinum-based therapy. Patients with EGFR mutant or ALK positive NSCLC should also have received targeted therapies before receiving tislelizumab.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Non-small cell lung cancer

Population group: only adults (18 years old or older)

Tislelizumab in combination with pemetrexed and platinum-containing chemotherapy is indicated for the first-line treatment of adult patients with non-squamous non-small cell lung cancer whose tumours have PD-L1 expression on ≥50% of tumour cells with no EGFR or ALK positive mutations and who have:

  • locally advanced NSCLC and are not candidates for surgical resection or platinum-based chemoradiation, or
  • metastatic NSCLC.

Tislelizumab in combination with carboplatin and either paclitaxel or nab-paclitaxel is indicated for the first-line treatment of adult patients with squamous non-small cell lung cancer who have:

  • locally advanced NSCLC and are not candidates for surgical resection or platinum-based chemoradiation, or
  • metastatic NSCLC.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Tislelizumab is contraindicated in the following cases:

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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