Trihexyphenidyl Other names: Trihexylphenizyl Triphenidyl

Chemical formula: C₂₀H₃₁NO  Molecular mass: 301.466 g/mol  PubChem compound: 5572

Interactions

Trihexyphenidyl interacts in the following cases:

G6PD deficiency

Deficiency of glucose-6-phosphate dehydrogenase

Glaucoma, obstructive disease of the gastro-intestinal or genito-urinary tract, prostatic hypertrophy

Trihexyphenidyl should be used with caution in patients with glaucoma, obstructive disease of the gastro-intestinal or genito-urinary tracts, and in elderly males with possible prostatic hypertrophy.

Pregnancy

There is inadequate information regarding the use of trihexyphenidyl in pregnancy. Animal studies are insufficient with regard to effects on pregnancy, embryonal/foetal development, parturition and postnatal development. The potential risk for humans is unknown. Trihexyphenidyl should not be used during pregnancy unless clearly necessary.

Nursing mothers

It is unknown whether trihexyphenidyl is excreted in human breast milk. The excretion of trihexyphenidyl in milk has not been studies in animals. Infants may be very sensitive to the effects of antimuscarinic medications. Trihexyphenidyl should not be used during breast-feeding.

Effects on ability to drive and use machines

Can cause blurring of vision, dizziness and mild nausea. Also mental confusion in some cases.

Cross-check medications

Review your medication to ensure that there are no potentially harmful drug interactions or contraindications.

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