Trihexyphenidyl Other names: Trihexylphenizyl Triphenidyl

Chemical formula: C₂₀H₃₁NO  Molecular mass: 301.466 g/mol  PubChem compound: 5572

Active ingredient description

Trihexyphenidyl is an anticholinergic agent. It is an antispasmodic drug which exerts a direct inhibitory effect on the parasympathetic nervous system. It diminishes salivation, increases the heart rate, dilates the pupils and reduces spasm of smooth muscle.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N04AA01 Trihexyphenidyl N Nervous system → N04 Anti-parkinson drugs → N04A Anticholinergic agents → N04AA Tertiary amines
Discover more medicines within N04AA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TRIHEXYPHENIDYL HYDROCHLORIDE Tablet FDA, National Drug Code (US) MPI, US: SPL/Old
TRIHEXYPHENIDYL Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 144-11-6
CAS Substance: 52-49-3
DrugBank Drug: DB00376
KEGG Drug: D08638
PubChem Compound: 5572
RxNorm Ingredient: 10811
SNOMED-CT Concept: 387120000
Trihexyphenidyl (substance)
UNII Identifier: 6RC5V8B7PO
TRIHEXYPHENIDYL

Medicines

Trihexyphenidyl is an active ingredient of these brands:

Australia (AU)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE

Brazil (BR)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE

Estonia (EE)

  • CYCLODOL as TRIHEXYPHENIDYL HYDROCHLORIDE

France (FR)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE
  • PARKINANE as TRIHEXYPHENIDYL HYDROCHLORIDE

Germany (DE)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE
  • PARKOPAN as TRIHEXYPHENIDYL HYDROCHLORIDE

Hong Kong (HK)

  • ARTANDYL as TRIHEXYPHENIDYL HYDROCHLORIDE

Israel (IL)

  • PARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE
  • RODENAL as TRIHEXYPHENIDYL HYDROCHLORIDE

Japan (JP)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE
  • PARKINES as TRIHEXYPHENIDYL HYDROCHLORIDE
  • SEDRENA as TRIHEXYPHENIDYL HYDROCHLORIDE

Lithuania (LT)

  • CYCLODOL as TRIHEXYPHENIDYL HYDROCHLORIDE
  • PARKOPAN as TRIHEXYPHENIDYL HYDROCHLORIDE

Malta (MT)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE

Mexico (MX)

Netherlands (NL)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE

Nigeria (NG)

  • AXZOL as TRIHEXYPHENIDYL HYDROCHLORIDE
  • CHEZXOL as TRIHEXYPHENIDYL HYDROCHLORIDE
  • EMBAZOL as TRIHEXYPHENIDYL HYDROCHLORIDE
  • HYZOL as TRIHEXYPHENIDYL HYDROCHLORIDE
  • OXAZOL as TRIHEXYPHENIDYL HYDROCHLORIDE
  • PBENZ as TRIHEXYPHENIDYL HYDROCHLORIDE

Romania (RO)

Singapore (SG)

Spain (ES)

  • ARTANE as TRIHEXYPHENIDYL HYDROCHLORIDE

Tunisia (TN)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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