Chemical formula: C₂₀H₂₉N₅O₃ Molecular mass: 387.484 g/mol PubChem compound: 5639
Urapidil is a α1-adrenoceptor antagonist and 5-HT1A receptor agonist and consequently inhibits the vasoconstrictor effect of catecholamines. It interacts with peripheral α1-adrenoceptors and central 5-HT1A receptors to produce vasodilation without sympathetic activation.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C02CA06 | Urapidil | C Cardiovascular system → C02 Antihypertensives → C02C Antiadrenergic agents, peripherally acting → C02CA Alpha-adrenoreceptor antagonists |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| URAPIDIL Solution for injection | MPI, EU: SmPC | ||
| URAPIDIL Prolonged-release capsule, hard | MPI, EU: SmPC |
Urapidil is an active ingredient of these brands:
Croatia (HR)Ecuador (EC)Estonia (EE)France (FR)
Germany (DE)Japan (JP)Lithuania (LT)Romania (RO)Spain (ES)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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