Chemical formula: C₂₄H₃₈N₂O₄ Molecular mass: 418.578 g/mol PubChem compound: 24795069
The mechanism of action of valbenazine for the treatment of tardive dyskinesia and chorea in patients with Huntington’s disease is unclear, but is thought to be mediated through the reversible inhibition of vesicular monoamine transporter 2 (VMAT2), a transporter that regulates monoamine uptake from the cytoplasm to the synaptic vesicle for storage and release.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N07XX13 | N Nervous system → N07 Other nervous system drugs → N07X Other nervous system drugs → N07XX Other nervous system drugs | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| INGREZZA Capsule | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Valbenazine is an active ingredient of these brands:
United States (US)Japan (JP)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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