Vardenafil

Chemical formula: C₂₃H₃₂N₆O₄S  Molecular mass: 488.603 g/mol  PubChem compound: 110634

Active ingredient description

Vardenafil is a potent and selective inhibitor of the cGMP specific phosphodiesterase type 5 (PDE5), the most prominent PDE in the human corpus cavernosum. Vardenafil is an oral therapy for the improvement of erectile function in men with erectile dysfunction. In the natural setting, i.e. with sexual stimulation it restores impaired erectile function by increasing blood flow to the penis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G04BE09 Vardenafil G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BE Drugs used in erectile dysfunction
Discover more medicines within G04BE09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VIVANZA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 224785-90-4
DrugBank Drug: DB00862
KEGG Drug: D08668
PubChem Compound: 110634
RxNorm Ingredient: 306674
SNOMED-CT Concept: 404858007
Vardenafil (substance)
UNII Identifier: UCE6F4125H
VARDENAFIL

Medicines

Vardenafil is an active ingredient of these brands:

United States (US)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE
  • STAXYN as VARDENAFIL HYDROCHLORIDE

Australia (AU)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Austria (AT)

Brazil (BR)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Canada (CA)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE
  • STAXYN as VARDENAFIL HYDROCHLORIDE

Cyprus (CY)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Ecuador (EC)

Estonia (EE)

Hong Kong (HK)

  • AVETRA as VARDENAFIL HYDROCHLORIDE
  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Ireland (IE)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE
  • VIVANZA as VARDENAFIL HYDROCHLORIDE

Israel (IL)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Italy (IT)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Lithuania (LT)

Mexico (MX)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Netherlands (NL)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

New Zealand (NZ)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Poland (PL)

Romania (RO)

Singapore (SG)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

South Africa (ZA)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Spain (ES)

  • LEVATIK as VARDENAFIL HYDROCHLORIDE
  • LEVITRA as VARDENAFIL HYDROCHLORIDE
  • SARILEN as VARDENAFIL HYDROCHLORIDE
  • VIVANZA as VARDENAFIL HYDROCHLORIDE

Turkey (TR)

United Kingdom (UK)

  • LEVITRA as VARDENAFIL HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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