Chemical formula: C₃₁H₄₆O₂ Molecular mass: 450.696 g/mol PubChem compound: 5284607
The presence of vitamin K (i.e. vitamin K or substances with vitamin K activity) is essential for the formation within the body of prothrombin, factor VII, factor IX and factor X. Lack of vitamin K leads to an increased tendency to haemorrhage. When an antidote to an anticoagulant is necessary it is essential to use vitamin K1 itself, as vitamin K analogues are much less effective.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B02BA01 | Phytomenadione | B Blood and blood forming organs → B02 Antihemorrhagics → B02B Vitamin K and other hemostatics → B02BA Vitamin K |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| KONAKION MM PAEDIATRIC Solution (ampoules) | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| KONAKION MM Solution (ampoules) | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Vitamin K1 is an active ingredient of these brands:
United States (US)
Australia (AU)
Brazil (BR)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)Finland (FI)France (FR)
Ireland (IE)
Israel (IL)
Lithuania (LT)Malta (MT)
Romania (RO)
South Africa (ZA)
Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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