Vitamin K1 Other names: alpha-Phylloquinone Phytylmenadione Phylloquinone Phytonadione Phytomenadione Phytylmenadione

Chemical formula: C₃₁H₄₆O₂  Molecular mass: 450.696 g/mol  PubChem compound: 5284607

Therapeutic indications

Vitamin K1 is indicated for:

Haemorrhage, associated with a low blood level of prothrombin or factor VII or anticoagulant drugs of the coumarin type

Population group: only adults (18 years old or older)

Vitamin K is indicated as an antidote to anticoagulant drugs of the coumarin type in the treatment of haemorrhage or threatened haemorrhage, associated with a low blood level of prothrombin or factor VII.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Haemorrhage, associated with a low blood level of prothrombin or factor VII or anticoagulant drugs of the coumarin type

Population group: only minors (0 - 18 years old)

Vitamin K is indicated as an antidote to anticoagulant drugs of the coumarin type in the treatment of haemorrhage or threatened haemorrhage, associated with a low blood level of prothrombin or factor VII.

Likely indications for using vitamin K in children are limited and may include:

  1. Children with disorders that interfere with absorption of vitamin K (chronic diarrhoea, cystic fibrosis, biliary atresia, hepatitis, coeliac disease).
  2. Children with poor nutrition who are receiving broad spectrum antibiotics.
  3. Liver disease.
  4. Patients receiving anticoagulant therapy with warfarin in whom the INR is increased outside the therapeutic range and therefore are at risk of, or are bleeding, and those with an INR in the therapeutic range who are bleeding.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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