Chemical formula: C₁₆H₂₄N₂ Molecular mass: 244.375 g/mol PubChem compound: 5709
Xylometazoline acts directly on α-adrenoreceptors but does not act on β-receptors. When used topically as a nasal decongestant, xylometazoline acts rapidly and provides long-lasting relief. Onset of action is within minutes, the decongestant effect being prolonged and lasting for up to 10 hours.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R01AA07 | Xylometazoline | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AA Sympathomimetics, plain |
| R01AB06 | Xylometazoline | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AB Sympathomimetics, combinations excl. corticosteroids |
| S01GA03 | Xylometazoline | S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GA Sympathomimetics used as decongestants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| SUDAFED NOSE SPRAY Aqueous solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Xylometazoline is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
Germany (DE)Hong Kong (HK)Ireland (IE)
Israel (IL)
Lithuania (LT)
Malta (MT)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)Poland (PL)
Romania (RO)
South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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