The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | J | Antiinfectives for systemic use | |
| 2 | J01 | Antibacterials for systemic use | |
| 3 | J01D | Other beta-lactam antibacterials | |
| 4 | J01DE | Fourth-generation cephalosporins | |
| 5 | J01DE51 |
| Active Ingredient | Description | |
|---|---|---|
| Cefepime and Enmetazobactam |
Cefepime exerts bactericidal activity by inhibiting peptidoglycan cell wall synthesis as a result of binding to and inhibition of penicillin-binding proteins (PBPs). Enmetazobactam is a penicillanic acid sulfone beta-lactamase inhibitor structurally related to penicillin. Enmetazobactam binds to β-lactamases and prevents the hydrolysis of cefepime. It is active against class A ESBLs. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| EXBLIFEP Powder for concentrate for solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC | |
| EXBLIFEP Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
