MENDICOF Syrup Ref.[28047] Active ingredients: Demorphan Dexchlorpheniramine Pseudoephedrine

Source: Health Sciences Authority (SG)  Revision Year: 2011  Publisher: <u>Manufacturer:</u> Sunward Pharmaceutical Sdn. Bhd., No. 9,11&17, Jalan Kempas 4, Taman Perindustrian Tampoi Indah, 81200 Johor Bahru, Johor, Malaysia. Tel: 07-2367531, 2367967, 2367972 Fax: 07-2367532 ...

Therapeutic indications

It is indicated for the relief of unproductive cough and nasal congestion due to common cold or allergy.

Posology and method of administration

Oral administration.

Adults and children above 12 years: 10 ml three times daily.

Children 6 to 12 years: 5 ml three times daily.

Overdose

Symptoms and Treatment for overdosage and antidote(s)

Dexchlorpheniramine overdosage effects may vary from central nervous system depression to stimulation to death. Toxic doses of pseudoephedrine may result in CNS stimulation, tachycardia, hypertension and cardiac arrhythmias; signs of CNS depression may occasionally be seen.

Dextromethorphan in toxic doses will cause drowsiness, ataxia, nystagmus, opisthotonos and convulsive seizures. Induce emesis if patient is alert and is seen prior to 6 hours following ingestion. Precautions against aspiration must be taken especially in infants and small children. Gastric lavage may be carried out although in some instances tracheostomy may be necessary prior to lavage. Naxolone hydrochloride 0.005 mg/kg intravenous short acting barbiturates may be indicated. Hypertensive responses and/or tachycardia should be treated appropriately. Oxygen, intravenous fluids and other supportive measures should be employed as indicated.

Shelf life

3 years.

Special precautions for storage

Store at temperature 25ยบC. Protect from light.

Nature and contents of container

Pack size: A bottle of 60ml, 100ml and 120ml.

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