Chemical formula: C₂₀H₃₄O₅ Molecular mass: 354.487 g/mol PubChem compound: 5280723
Alprostadil is chemically identical to prostaglandin E1, the actions of which include vasodilatation of blood vessels in the erectile tissues of the corpora cavernosa and increase in cavernosal artery blood flow, causing penile rigidity.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01EA01 | Alprostadil | C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EA Prostaglandins |
| G04BE01 | Alprostadil | G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BE Drugs used in erectile dysfunction |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MUSE Urethral Stick | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PROSTIN VR Concentrate for solution for infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| CAVERJECT Powder for solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Alprostadil is an active ingredient of these brands:
United States (US)Australia (AU)Austria (AT)
Brazil (BR)
Canada (CA)Croatia (HR)Ecuador (EC)Estonia (EE)France (FR)Hong Kong (HK)Israel (IL)Japan (JP)Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)New Zealand (NZ)Poland (PL)
Romania (RO)Singapore (SG)South Africa (ZA)Tunisia (TN)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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