Ceftaroline fosamil

Chemical formula: C₂₂H₂₁N₈O₈PS₄  Molecular mass: 684.67 g/mol  PubChem compound: 9852981

Active ingredient description

In vitro studies have shown that ceftaroline is bactericidal and able to inhibit bacterial cell wall synthesis in methicillin-resistant Staphylococcus aureus (MRSA) and penicillin non-susceptible Streptococcus pneumoniae (PNSP) due to its affinity for the altered penicillin-binding proteins (PBPs) found in these organisms. As a result, minimum inhibitory concentrations (MICs) of ceftaroline against a proportion of these organisms tested fall into the susceptible range.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01DI02 J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DI Other cephalosporins
Discover more medicines within J01DI02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ZINFORO Powder for concentrate for solution European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 229016-73-3
DrugBank Drug: DB06590
KEGG Drug: D08884
PubChem Compound: 9852981
RxNorm Ingredient: 1040004
SNOMED-CT Concept: 702415007
Ceftaroline fosamil (substance)
UNII Identifier: 7P6FQA5D21
CEFTAROLINE FOSAMIL

Medicines

Ceftaroline fosamil is an active ingredient of these brands:

United States (US)

Austria (AT)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Brazil (BR)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Croatia (HR)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Cyprus (CY)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Estonia (EE)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Finland (FI)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

France (FR)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Hong Kong (HK)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Ireland (IE)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Israel (IL)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Italy (IT)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Lithuania (LT)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Netherlands (NL)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

New Zealand (NZ)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Poland (PL)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Romania (RO)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Singapore (SG)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

South Africa (ZA)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Spain (ES)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Tunisia (TN)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

United Kingdom (UK)

  • ZINFORO as Ceftaroline fosamil acetic acid solvate monohydrate

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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