Ciprofloxacin

Chemical formula: C₁₇H₁₈FN₃O₃  Molecular mass: 331.342 g/mol  PubChem compound: 2764

Active ingredient description

Ciprofloxacin is a fluoroquinolone antibacterial agent. The bactericidal action of ciprofloxacin results from the inhibition of both type II topoisomerase (DNA-gyrase) and topoisomerase IV, required for bacterial DNA replication, transcription, repair and recombination.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01MA02 Ciprofloxacin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01M Quinolone antibacterials → J01MA Fluoroquinolones
Discover more medicines within J01MA02
S01AE03 S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AE Fluoroquinolones
Discover more medicines within S01AE03
S02AA15 Ciprofloxacin S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives
Discover more medicines within S02AA15
S03AA07 Ciprofloxacin S Sensory organs → S03 Ophthalmological and otological preparations → S03A Antiinfectives → S03AA Antiinfectives
Discover more medicines within S03AA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CIPROFLOXACIN Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CILOXAN Eye drops, solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CILOXAN Ointment FDA, National Drug Code (US) MPI, US: SPL/Old
CIPROFLOXACIN Solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CILOXAN Ophthalmic solution FDA, National Drug Code (US) MPI, US: SPL/Old
CIPRO Film-coated tablet / Oral suspension kit FDA, National Drug Code (US) MPI, US: SPL/PLR
CETRAXAL Ear drops Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 85721-33-1
CAS Substance: 86393-32-0
CAS Substance: 97867-33-9
DrugBank Drug: DB00537
KEGG Drug: D00186
PubChem Compound: 2764
RxNorm Ingredient: 2551
SNOMED-CT Concept: 372840008
Ciprofloxacin (substance)
UNII Identifier: 5E8K9I0O4U
CIPROFLOXACIN

Medicines

Ciprofloxacin is an active ingredient of these brands:

United States (US)

  • CETRAXAL as CIPROFLOXACIN HYDROCHLORIDE
  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPRO as CIPROFLOXACIN HYDROCHLORIDE
  • OTIPRIO
  • (combination) CIPRO HC as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) CIPRODEX as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) OTOVEL

Albania (AL)

Australia (AU)

Austria (AT)

  • CIFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROMED as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROSTAD as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROXIN as Ciprofloxacin hydrochloride monohydrate
  • OTANOL as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) INFECTOCIPROCORT as Ciprofloxacin hydrochloride hydrate

Brazil (BR)

Canada (CA)

  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPRO as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) CIPRODEX as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) OTIXAL as CIPROFLOXACIN HYDROCHLORIDE

Croatia (HR)

  • CIFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPRINOL as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROMED as CIPROFLOXACIN HYDROCHLORIDE
  • CITERAL as CIPROFLOXACIN HYDROCHLORIDE

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

  • CIFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • UNIFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) CILOXADEX as CIPROFLOXACIN HYDROCHLORIDE

Germany (DE)

  • CIPRO as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROBETA as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROHEXAL as CIPROFLOXACIN HYDROCHLORIDE

Hong Kong (HK)

  • APROCIN as CIPROFLOXACIN HYDROCHLORIDE
  • ARISTIN-C as Ciprofloxacin hydrochloride monohydrate
  • BAQUINOR as CIPROFLOXACIN HYDROCHLORIDE
  • CIFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • CIPIDE as CIPROFLOXACIN HYDROCHLORIDE
  • CIPMAX as CIPROFLOXACIN HYDROCHLORIDE
  • CIPQUIN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROCIN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROCINA as CIPROFLOXACIN LACTATE
  • CIPROL as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROVICK as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROXIN as Ciprofloxacin hydrochloride monohydrate
  • CIPROXYL as CIPROFLOXACIN HYDROCHLORIDE
  • CIROK
  • CIVELL as CIPROFLOXACIN HYDROCHLORIDE
  • COBAY as CIPROFLOXACIN HYDROCHLORIDE
  • CYFLOXIN as CIPROFLOXACIN HYDROCHLORIDE
  • CYPLOX as CIPROFLOXACIN HYDROCHLORIDE
  • FLONTIN as CIPROFLOXACIN HYDROCHLORIDE
  • GIROFLOX
  • GONNING as CIPROFLOXACIN HYDROCHLORIDE
  • HIPPRO as CIPROFLOXACIN HYDROCHLORIDE
  • INTERFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • LOXIN as CIPROFLOXACIN HYDROCHLORIDE
  • MEDOCIPRIN
  • MICROCIP as CIPROFLOXACIN HYDROCHLORIDE
  • OCUFLUOR as CIPROFLOXACIN HYDROCHLORIDE
  • PROXACIN as CIPROFLOXACIN HYDROCHLORIDE
  • QUIDEX as CIPROFLOXACIN HYDROCHLORIDE
  • QUINTOR as CIPROFLOXACIN HYDROCHLORIDE
  • ROSACIN as CIPROFLOXACIN HYDROCHLORIDE
  • TOPISTIN as Ciprofloxacin hydrochloride monohydrate
  • TROXECIN as CIPROFLOXACIN HYDROCHLORIDE
  • UFEXIL
  • UROXIN as CIPROFLOXACIN HYDROCHLORIDE
  • UTAHZONE as CIPROFLOXACIN HYDROCHLORIDE
  • VESPROCIN as CIPROFLOXACIN HYDROCHLORIDE
  • VIPROLOX as CIPROFLOXACIN HYDROCHLORIDE
  • VOLINOL as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) CETRAXAL PLUS as CIPROFLOXACIN HYDROCHLORIDE

Ireland (IE)

Israel (IL)

Italy (IT)

  • BASEMAR as CIPROFLOXACIN HYDROCHLORIDE
  • BATTIZER as CIPROFLOXACIN HYDROCHLORIDE
  • BOSIX as CIPROFLOXACIN HYDROCHLORIDE
  • CHINOCID as CIPROFLOXACIN HYDROCHLORIDE
  • CIPERUS as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROXIN as Ciprofloxacin hydrochloride monohydrate
  • CUSPIS as CIPROFLOXACIN HYDROCHLORIDE
  • EOXIN as CIPROFLOXACIN HYDROCHLORIDE
  • FLONTALEXIN
  • GENERFLON
  • GERBAT as CIPROFLOXACIN HYDROCHLORIDE
  • IBIXACIN as CIPROFLOXACIN HYDROCHLORIDE
  • MACAR as CIPROFLOXACIN HYDROCHLORIDE
  • PROCIFLOR as CIPROFLOXACIN HYDROCHLORIDE
  • SAMPER as CIPROFLOXACIN HYDROCHLORIDE
  • ULLAX as CIPROFLOXACIN HYDROCHLORIDE

Japan (JP)

  • CIPROXAN as CIPROFLOXACIN HYDROCHLORIDE

Lithuania (LT)

Malta (MT)

Mexico (MX)

  • (combination) OTO ENI as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) VODELAN as CIPROFLOXACIN HYDROCHLORIDE

Netherlands (NL)

  • CIPROXIN as Ciprofloxacin hydrochloride monohydrate

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

  • CIFRAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPRINOL as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROCIN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROLEN as CIPROFLOXACIN HYDROCHLORIDE
  • CUMINOL as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) CEXIDAL as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) OTOTIS as CIPROFLOXACIN HYDROCHLORIDE

Singapore (SG)

  • C-FLOX as CIPROFLOXACIN HYDROCHLORIDE
  • CETRAXAL as CIPROFLOXACIN HYDROCHLORIDE
  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPLUS as CIPROFLOXACIN HYDROCHLORIDE
  • CIPRO as CIPROFLOXACIN HYDROCHLORIDE
  • CIROK
  • CYCIN as CIPROFLOXACIN HYDROCHLORIDE
  • ENOXIN as CIPROFLOXACIN HYDROCHLORIDE
  • MICROFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • NEOFLOXIN
  • NOVAFLOX as CIPROFLOXACIN HYDROCHLORIDE
  • POLI-CIFLOXIN as Ciprofloxacin hydrochloride monohydrate
  • QUPRON as CIPROFLOXACIN HYDROCHLORIDE
  • TOPISTIN as Ciprofloxacin hydrochloride monohydrate
  • VIPROLOX as CIPROFLOXACIN HYDROCHLORIDE
  • (combination) CILODEX as CIPROFLOXACIN HYDROCHLORIDE

South Africa (ZA)

  • BIOCIP as CIPROFLOXACIN HYDROCHLORIDE
  • BIOFLOXX as CIPROFLOXACIN HYDROCHLORIDE
  • CEPROLEN as CIPROFLOXACIN HYDROCHLORIDE
  • CIFLOC as CIPROFLOXACIN HYDROCHLORIDE
  • CIFRAN as CIPROFLOXACIN HYDROCHLORIDE
  • CILOFLOC as CIPROFLOXACIN HYDROCHLORIDE
  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPLOXX as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROCHEM as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROCINA as CIPROFLOXACIN LACTATE
  • CIPRODAC as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROGEN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROHEXAL as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROL as CIPROFLOXACIN HYDROCHLORIDE
  • COLIPRID as CIPROFLOXACIN HYDROCHLORIDE
  • CYFLOC as CIPROFLOXACIN HYDROCHLORIDE
  • DYNAFLOC as CIPROFLOXACIN HYDROCHLORIDE
  • FLOPRO as CIPROFLOXACIN HYDROCHLORIDE
  • FLOQIN as CIPROFLOXACIN LACTATE
  • FOXIN as CIPROFLOXACIN HYDROCHLORIDE
  • LOXIP
  • OCIP as CIPROFLOXACIN HYDROCHLORIDE
  • ORPIC
  • PROFLOXIN as CIPROFLOXACIN HYDROCHLORIDE
  • XINOCT as CIPROFLOXACIN HYDROCHLORIDE

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

  • CETRAXAL as CIPROFLOXACIN HYDROCHLORIDE
  • CILOXAN as CIPROFLOXACIN HYDROCHLORIDE
  • CIPROXIN as Ciprofloxacin hydrochloride monohydrate
  • (combination) CETRAXAL PLUS as CIPROFLOXACIN HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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