Clarithromycin
Chemical formula: C₃₈H₆₉NO₁₃ Molecular mass: 747.953 g/mol PubChem compound: 84029
Active ingredient description
Clarithromycin is a semi-synthetic derivative of erythromycin A. It exerts its antibacterial action by selectively binding to the 50s ribosomal sub-unit of susceptible bacteria preventing translocation of activated amino acids. It inhibits the intracellular protein synthesis of susceptible bacteria.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| J01FA09 | Clarithromycin | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01F Macrolides, lincosamides and streptogramins → J01FA Macrolides |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| CLARITHROMYCIN Film-coated tablets | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| KLERIMED Film coated tablet | MPI, EU: SmPC | Υπουργείο Υγείας (CY) | |
| CLARITHROMYCIN Powder for concentrate for solution for infusion | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Clarithromycin is an active ingredient of these brands:
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