Ethambutol

Chemical formula: C₁₀H₂₄N₂O₂  Molecular mass: 204.31 g/mol  PubChem compound: 14052

Active ingredient description

Ethambutol is bacteriostatic. It is effective against Mycobacterium tuberculosi and M.bovis with an MIC of 0.5–8µg per ml. The exact mechanism of action is unknown. While it has activity against some atypical mycobacteria including M.Kansasii, activity against other micro-organisms has not yet been reported.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J04AK02 Ethambutol J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AK Other drugs for treatment of tuberculosis
Discover more medicines within J04AK02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MYAMBUTOL Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/Old
ETHAMBUTOL Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ETIBI Tablet Health Products and Food Branch (CA) MPI, CA: SPM

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 74-55-5
DrugBank Drug: DB00330
KEGG Drug: D07925
PubChem Compound: 14052
RxNorm Ingredient: 4110
SNOMED-CT Concept: 387129004
Ethambutol (substance)
UNII Identifier: 8G167061QZ
ETHAMBUTOL

Medicines

Ethambutol is an active ingredient of these brands:

United States (US)

Austria (AT)

  • ETIBI as ETHAMBUTOL HYDROCHLORIDE
  • MYAMBUTOL as ETHAMBUTOL HYDROCHLORIDE

Canada (CA)

  • ETIBI as ETHAMBUTOL HYDROCHLORIDE

Estonia (EE)

France (FR)

Hong Kong (HK)

Japan (JP)

  • EBUTOL as ETHAMBUTOL HYDROCHLORIDE

Malta (MT)

Mexico (MX)

  • BRUNIBUTOL as ETHAMBUTOL HYDROCHLORIDE

  • (combination) DOTBAL as ETHAMBUTOL HYDROCHLORIDE

Netherlands (NL)

Nigeria (NG)

  • (combination) AKT-4 as ETHAMBUTOL HYDROCHLORIDE

Singapore (SG)

  • E-BUTOL as ETHAMBUTOL HYDROCHLORIDE
  • EBUTOL as ETHAMBUTOL HYDROCHLORIDE

South Africa (ZA)

  • PURDERAL as ETHAMBUTOL HYDROCHLORIDE
  • THAMTOL as ETHAMBUTOL HYDROCHLORIDE

  • (combination) KOXIRIP
  • (combination) MYRIN as ETHAMBUTOL HYDROCHLORIDE
  • (combination) MYRIN PLUS as ETHAMBUTOL HYDROCHLORIDE
  • (combination) MYRIN-P FORTE
  • (combination) PURDERAL CO as ETHAMBUTOL HYDROCHLORIDE
  • (combination) RIFAFOUR e-275 as ETHAMBUTOL HYDROCHLORIDE
  • (combination) RIMTIB as ETHAMBUTOL HYDROCHLORIDE
  • (combination) RISOPET as ETHAMBUTOL HYDROCHLORIDE
  • (combination) RITIB as ETHAMBUTOL HYDROCHLORIDE

Spain (ES)

  • MYAMBUTOL as ETHAMBUTOL HYDROCHLORIDE

  • (combination) RIMSTAR as ETHAMBUTOL HYDROCHLORIDE

Turkey (TR)

United Kingdom (UK)

  • (combination) VORACTIV as ETHAMBUTOL HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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