Chemical formula: C₁₃H₁₂F₂N₆O Molecular mass: 306.271 g/mol PubChem compound: 3365
Fluconazole is a triazole antifungal agent. Its primary mode of action is the inhibition of fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D01AC15 | Fluconazole | D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AC Imidazole and triazole derivatives |
| J02AC01 | Fluconazole | J Antiinfectives for systemic use → J02 Antimycotics for systemic use → J02A Antimycotics for systemic use → J02AC Triazole and tetrazole derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DIFLUCAN Solution for infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DIFLUCAN Hard capsule | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DIFLUCAN Tablet / Oral suspension | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Fluconazole is an active ingredient of these brands:
United States (US)Brazil (BR)Canada (CA)
Cyprus (CY)Ecuador (EC)
Finland (FI)Hong Kong (HK)Israel (IL)Italy (IT)Japan (JP)Malta (MT)Netherlands (NL)New Zealand (NZ)Nigeria (NG)Singapore (SG)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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