Chemical formula: C₂₁H₁₉N₃O₅ Molecular mass: 393.132 g/mol PubChem compound: 44480399
Fruquintinib is a selective tyrosine kinase inhibitor of VEGFR-1, -2, and -3 with antitumor effects resulting from suppression of tumour angiogenesis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01EK04 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| FRUZAQLA Hard capsule | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| FRUZAQLA Hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC |
Fruquintinib is an active ingredient of these brands:
United States (US)Austria (AT)France (FR)Lithuania (LT)Romania (RO)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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