Linezolid

Chemical formula: C₁₆H₂₀FN₃O₄  Molecular mass: 337.346 g/mol  PubChem compound: 441401

Active ingredient description

Linezolid is a synthetic, antibacterial agent that belongs to a new class of antimicrobials, the oxazolidinones. It has in vitro activity against aerobic Gram-positive bacteria and anaerobic micro-organisms. Linezolid selectively inhibits bacterial protein synthesis via a unique mechanism of action.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01XX08 Linezolid J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01X Other antibacterials → J01XX Other antibacterials
Discover more medicines within J01XX08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LINEZOLID Solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ZYVOX Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR
LINEZOLID Film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 165800-03-3
DrugBank Drug: DB00601
KEGG Drug: D00947
PubChem Compound: 441401
RxNorm Ingredient: 190376
SNOMED-CT Concept: 387056004
Linezolid (substance)
UNII Identifier: ISQ9I6J12J
LINEZOLID

Medicines

Linezolid is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Estonia (EE)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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