Chemical formula: C₁₄H₂₁N₃O₂S Molecular mass: 295.4 g/mol PubChem compound: 5358
Sumatriptan has been demonstrated to be a specific and selective 5-Hydroxytryptamine1 (5HT1D) receptor agonist with no effect on other 5HT receptor (5-HT2 - 5-HT7) subtypes. The vascular 5-HT1D receptor is found predominantly in cranial blood vessels and mediates vasoconstriction.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N02CC01 | Sumatriptan | N Nervous system → N02 Analgesics → N02C Antimigraine preparations → N02CC Selective serotonin (5HT1) agonists |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| IMIGRAN Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| IMITREX Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| IMIGRAN Nasal spray, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| IMITREX Nasal spray | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| IMITREX Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| IMIGRAN Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Sumatriptan is an active ingredient of these brands:
United States (US)
Austria (AT)
Brazil (BR)Cyprus (CY)
Ecuador (EC)
Germany (DE)
Hong Kong (HK)
Israel (IL)
Italy (IT)
Japan (JP)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)Poland (PL)Romania (RO)South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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