Chemical formula: C₁₆H₂₀N₄O₃S Molecular mass: 348.42 g/mol PubChem compound: 41781
Torasemide is a loop diuretic. Torasemide acts as a salidiuretic by inhibition of renal sodium and chloride reabsorption in the ascending limb of the loop of Henle. Torasemide leads to a gentle removal of edema and especially to an improvement of the working condition of the heart failure by reducing the preload and afterload. In patients with severe to endstage chronic renal failure there is a reduction of aterial blood pressure in addition to removal of edema and maintenance of residual diuresis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03CA04 | Torasemide | C Cardiovascular system → C03 Diuretics → C03C High-ceiling diuretics → C03CA Sulfonamides, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| TOREM 5mg Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| TOREM 2.5mg Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| TOREM 10mg Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Torasemide is an active ingredient of these brands:
Japan (JP)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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