ATC Group: C08DA Phenylalkylamine derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of C08DA in the ATC hierarchy

Level Code Title
1 C Cardiovascular system
2 C08 Calcium channel blockers
3 C08D Selective calcium channel blockers with direct cardiac effects
4 C08DA Phenylalkylamine derivatives

Group C08DA contents

Code Title
C08DA01 Verapamil
C08DA02 Gallopamil
C08DA51 Verapamil, combinations

Active ingredients in C08DA

Active Ingredient Description
Verapamil

Verapamil inhibits the transmembrane influx of calcium ions into the heart and vascular smooth muscle cell. The myocardial oxygen demand is lowered directly as a result of the effect on the energy consuming metabolic processes of the myocardial cell and indirectly due to a reduction of the afterload. Due to its effect on coronary vascular smooth muscle, verapamil enhances myocardial blood flow, even in post‐stenotic areas, and relieves coronary spasms. These properties contribute to the anti‐ischaemic and antianginal efficacy of verapamil in all types of coronary artery disease.

Related product monographs

Title Information Source Document Type  
AKILEN Film-coated tablet Υπουργείο Υγείας (CY) MPI, EU: SmPC
ISOPTIN Film‐coated tablet Health Products Regulatory Authority (IE) MPI, EU: SmPC
ISOPTIN Solution for injection / infusion Health Products Regulatory Authority (IE) MPI, EU: SmPC
SECURON Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
SECURON SR Modified-release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
VERAPAMIL Oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC