Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'S'

Indication Treatments
Salt-losing congenital adrenal hyperplasia
Fludrocortisone : Salt-losing adrenogenital syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Sarcoidosis
Prednisolone : Sarcoidosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Sarcoma of soft tissue
22-Oxovincaleukoblastine : Soft tissue sarcoma – only adults (18 years old or older)
Dacarbazine : Soft tissue sarcoma – only adults (18 - 65 years old)
Melphalan : Soft tissue sarcoma – only adults (18 years old or older)
Olaratumab : Soft tissue sarcoma – only adults (18 years old or older)
Pazopanib : Soft-tissue sarcoma (STS) – only adults (18 years old or older)
Trabectedin : Soft tissue sarcoma – only adults (18 years old or older)
Sarcoptes scabiei
Afoxolaner : Sarcotopic scabies
Saturnine poisoning
Calcium gluconate : Fluoride poisoning, lead poisoning – only adults (18 years old or older)
Scabies
Ivermectin : Human sarcoptic scabies – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Permethrin : Scabies – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Permethrin : Scabies, crab lice – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Phenothrin : Scabies, crab lice – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Scald of skin
Chlorhexidine : Burns, scalds, scratches, cuts, abrasions, sunburn blisters, infected cracked skin – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Scalp psoriasis
Calcipotriol : Psoriasis vulgaris – only adults (18 years old or older)
Clobetasol propionate : Scalp psoriasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Scanty tear production
Acetylcysteine : Deficient tear secretion – only adults (18 - 65 years old)
Schizoaffective disorder
Haloperidol : Schizoaffective disorder – only elderly (65 years old or older)
Haloperidol : Schizoaffective disorder – only adults (18 - 65 years old)
Paliperidone : Schizoaffective disorder – only adults (18 - 65 years old)
Schizophrenia
Aripiprazole : Schizophrenia – only adolescents (12 years - 18 years old)
Aripiprazole : Schizophrenia – only adults (18 years old or older)
Brexpiprazole : Schizophrenia – only adults (18 - 65 years old)
Chlorpromazine : Schizophrenia, autism – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Chlorpromazine : Schizophrenia, mania, hypomania – only elderly (65 years old or older)
Chlorpromazine : Schizophrenia, mania, hypomania – only adults (18 - 65 years old)
Clozapine : Treatment-resistant schizophrenia – only adults (18 years old or older)
Haloperidol : Schizophrenia – only adolescents (12 years - 18 years old)
Haloperidol : Schizophrenia – only elderly (65 years old or older)
Haloperidol : Schizophrenia – only adults (18 - 65 years old)
Iloperidone : Schizophrenia – only adults (18 years old or older)
Levomepromazine : Schizophrenia – only adults (18 - 65 years old)
Levosulpiride : Acute schizophrenia – only adults (18 years old or older)
Lurasidone : Schizophrenia – only adolescents (12 years - 18 years old)
Lurasidone : Schizophrenia – only adults (18 years old or older)
Olanzapine : Schizophrenia – only elderly (65 years old or older)
Olanzapine : Schizophrenia – only adults (18 - 65 years old)
Paliperidone : Schizophrenia – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Perphenazine : Schizophrenia – only adults (18 - 65 years old)
Quetiapine : Schizophrenia, moderate to severe manic episodes in bipolar disorder – only adults (18 years old or older)
Risperidone : Schizophrenia – only adults (18 - 65 years old)
Risperidone : Schizophrenia – only elderly (65 years old or older)
Ziprasidone : Schizophrenia – only adults (18 years old or older)
Zuclopenthixol : Schizophrenia, psychoses – only adults (18 years old or older)
Scleritis
Dexamethasone : Scleritis – only adults (18 years old or older)
Prednisolone : Scleritis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Scratch marks
Chlorhexidine : Burns, scalds, scratches, cuts, abrasions, sunburn blisters, infected cracked skin – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Seborrheic dermatitis
Betamethasone : Seborrhoeic dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ciclopirox olamine : Seborrhoeic dermatitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Fluocinonide : Seborrheic dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ketoconazole : Seborrheic dermatitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Seborrheic dermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Secondary amenorrhea
Medroxyprogesterone : Secondary amenorrhoea – women, only adults (18 - 65 years old)
Secondary angle-closure glaucoma
Acetazolamide : Secondary or acute narrow angle glaucoma – only adults (18 years old or older)
Secondary gout
Lesinurad : Hyperuricaemia in gout – only adults (18 years old or older)
Secondary hypocortisolism
Dexamethasone : Secondary adrenocortical insufficiency – only adults (18 years old or older)
Fludrocortisone : Secondary adrenocortical insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Secondary adrenocortical insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Secondary immune deficiency disorder
Human normal immunoglobulin G : Primary immunodeficiency syndromes with impaired antibody production, secondary immunodeficiencies (SID) – only minors (0 - 18 years old) , adults (18 - 65 years old)
Immunoglobulins, normal human, IV : Secondary immunodeficiencies – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Secondary malignant neoplasm of brain
Carmustine : Glioblastoma, brain-stem gliomas, medulloblastoma, astrocytoma, ependymoma, brain metastases – only adults (18 years old or older)
Secondary malignant neoplasm of cecum and/or colon and/or rectum
Fruquintinib : Metastatic colorectal cancer – only adults (18 years old or older)
Secondary open-angle glaucoma
Carteolol : Ocular hypertension, chronic open angle glaucoma, secondary glaucomas – only adults (18 years old or older)
Secondary progressive multiple sclerosis
Siponimod : Secondary progressive multiple sclerosis (SPMS)
Secondary syphilis
Doxycycline : Primary and secondary syphilis – only adults (18 years old or older)
Sedation
Alfentanil : Analgesia, suppression of respiratory activity – only adults (18 - 65 years old)
Midazolam : Sedation during minor medical procedures – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Midazolam : Sedation during minor medical procedures – only elderly (65 years old or older)
Midazolam : Sedation during minor medical procedures – only adults (18 - 65 years old)
Midazolam : Sedation in intensive care – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Promethazine : Sedation – only adults (18 - 65 years old)
Remimazolam : Procedural sedation – only adults (18 years old or older)
Seizure
Midazolam : Prolonged, acute, convulsive seizures – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Seizure disorder
Clonazepam : Seizure – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
Clonazepam : Seizure – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Clonazepam : Seizure – only elderly (65 years old or older)
Clonazepam : Seizure – only adults (18 - 65 years old)
Senile atrophic vaginitis
Estradiol : Atrophic vaginitis in menopause – only adults (18 - 65 years old)
Estriol : Atrophic vaginitis – women, only adults (18 years old or older)
Ospemifene : Moderate to severe symptomatic vulvar and vaginal atrophy (VVA) in post-menopausal women – women, only adults (18 years old or older)
Prasterone : Vulvar and vaginal atrophy in postmenopausal women having moderate to severe symptoms – women, only adults (18 years old or older)
Senile cardiac amyloidosis
Tafamidis : Transthyretin amyloidosis – only adults (18 - 65 years old)
Senile degeneration of brain
Meclofenoxate : Cerebral aging – only adults (18 years old or older)
Senile hyperkeratosis
Fluorouracil : Pre-malignant and malignant skin lesions – only adults (18 years old or older)
Sensation of irritation of eye proper
Naphazoline : Eye irritation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Septic shock
Dobutamine : Cardiac decompensation, disturbed ventricular function – only minors (0 - 18 years old)
Dobutamine : Cardiac decompensation, disturbed ventricular function – only adults (18 years old or older)
Sequelae of injuries of head
Meclofenoxate : Neurological or psychological sequelea of head injury – only adults (18 years old or older)
Seronegative arthritis
Ibuprofen : Seronegative arthritis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Serum sickness caused by drug
Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Hydrocortisone : Serum sickness – only minors (0 - 18 years old) , adults (18 years old or older)
Methylprednisolone : Serum sickness caused by drug – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Serum sickness caused by drug – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Severe anxiety (panic)
Lorazepam : Severe anxiety – only elderly (65 years old or older)
Lorazepam : Severe anxiety – only adults (18 - 65 years old)
Severe asthma
Dupilumab : Severe asthma with type 2 inflammation – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Tezepelumab : Severe asthma inadequately controlled – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Severe bipolar I disorder, single manic episode with psychotic features
Quetiapine : Schizophrenia, moderate to severe manic episodes in bipolar disorder – only adults (18 years old or older)
Severe bipolar I disorder, single manic episode without psychotic features
Quetiapine : Schizophrenia, moderate to severe manic episodes in bipolar disorder – only adults (18 years old or older)
Severe chronic obstructive pulmonary disease
Roflumilast : Severe chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis – only adults (18 years old or older)
Severe haemophilia B without inhibitor
Etranacogene dezaparvovec : Severe and moderately severe Haemophilia B without Factor IX inhibitors – only adults (18 years old or older)
Fidanacogene elaparvovec : Moderate to severe hemophilia B – men, only adults (18 - 65 years old)
Severe hemophilia A
Emicizumab : Haemophilia A with factor VIII inhibitors, severe haemophilia A – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Valoctocogene roxaparvovec : Severe haemophilia A – only adults (18 years old or older)
Severe major depression
Fluoxetine : Moderate to severe major depressive episode – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Severe manic bipolar I disorder with psychotic features
Asenapine : Moderate to severe manic episodes associated with bipolar I disorder – only adults (18 years old or older)
Severe manic bipolar I disorder without psychotic features
Asenapine : Moderate to severe manic episodes associated with bipolar I disorder – only adults (18 years old or older)
Severe myoclonic epilepsy in infancy
Cannabidiol : Seizures associated with Lennox-Gastaut syndrome or Dravet syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Stiripentol : Severe myoclonic epilepsy in infancy (SMEI, Dravet's syndrome) – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Severe pain
Buprenorphine : Severe pain – only adults (18 years old or older)
Ethanol : Severe and chronic pain – only adults (18 years old or older)
Morphine : Severe pain – only children (1 year - 12 years old)
Morphine : Severe pain – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Nalbuphine : Moderate to severe pain, postoperative pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Nalbuphine : Moderate to severe pain, postoperative pain – only adults (18 years old or older)
Oxycodone : Severe pain which requires long-term opioid treatment – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Pethidine : Moderate to severe pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Pethidine : Moderate to severe pain – only elderly (65 years old or older)
Pethidine : Moderate to severe pain – only adults (18 - 65 years old)
Tapentadol : Moderate to severe acute pain – only adults (18 years old or older)
Tramadol : Moderate to severe pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Severe persistent asthma
Mometasone : Severe persistent asthma – only adults (18 years old or older)
Severe pre-eclampsia
Nicardipine : Severe pre-eclampsia – women, only adults (18 - 65 years old)
Severe pulmonary hypertension
Iloprost : Primary pulmonary hypertension, classified as NYHA functional class III – only adults (18 years old or older)
Sézary's disease
Mogamulizumab : Sézary syndrome (SS) – only adults (18 - 65 years old)
Shock
Betamethasone : Severe shock – only children (1 year - 12 years old)
Betamethasone : Severe shock – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Dexamethasone : Shock – only adults (18 years old or older)
Hydrocortisone : Shock – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Hydrocortisone : Shock – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Short bowel syndrome
Cimetidine : Short bowel syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Cimetidine : Short bowel syndrome – only infants (40 days - 1 year old)
Cimetidine : Short bowel syndrome – only adults (18 years old or older)
Teduglutide : Short Bowel Syndrome (SBS) – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Shoulder pain
Oxaprozin : Shoulder pain
Sickle cell anemia
Thiotepa : Sickle cell anaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Sickling disorder due to hemoglobin S
Exagamglogene autotemcel : Sickle cell disease – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Voxelotor : Haemolytic anaemia due to sickle cell disease (SCD) – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Simple pulmonary alveolitis
Prednisolone : Pulmonary alveolitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Single manic episode, moderate
Olanzapine : Moderate to severe manic episode – only elderly (65 years old or older)
Olanzapine : Moderate to severe manic episode – only adults (18 - 65 years old)
Single manic episode, severe, with psychosis
Olanzapine : Moderate to severe manic episode – only elderly (65 years old or older)
Olanzapine : Moderate to severe manic episode – only adults (18 - 65 years old)
Singultus
Chlorpromazine : Intractable hiccup – only elderly (65 years old or older)
Chlorpromazine : Intractable hiccup – only adults (18 - 65 years old)
Sinus tachycardia
Landiolol : Sinus tachycardia – only adults (18 - 65 years old)
Sinusitis
Serrapeptase : Sinusitis – only adults (18 years old or older)
Skin fissure
Dexpanthenol : Superficial skin lesion, skin inflammation
SLE glomerulonephritis syndrome
Belimumab : Active lupus nephritis – only adults (18 years old or older)
Cyclophosphamide : Severe progressive forms of lupus nephritis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Lupus nephritis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
SLE glomerulonephritis syndrome, WHO class III
Voclosporin : Class III, IV or V lupus nephritis – only adults (18 years old or older)
SLE glomerulonephritis syndrome, WHO class IV
Voclosporin : Class III, IV or V lupus nephritis – only adults (18 years old or older)
SLE glomerulonephritis syndrome, WHO class V
Voclosporin : Class III, IV or V lupus nephritis – only adults (18 years old or older)
Sleep-wake schedule disorder due to jet lag
Promethazine : Temporary disturbances of sleep pattern – only adults (18 years old or older)
Small bowel fistula
Lanreotide : Postoperative pancreatic fistula, postoperative small bowel fistula – only adults (18 years old or older)
Small cell carcinoma of lung
22-Oxovincaleukoblastine : Small cell bronchogenic carcinoma – only adults (18 years old or older)
Atezolizumab : Small cell carcinoma of lung – only adults (18 years old or older)
Carboplatin : Small cell carcinoma of the lung – only adults (18 years old or older)
Cis-Diaminedichloroplatinum : Small cell carcinoma of lung – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cyclophosphamide : Small cell lung cancer – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Durvalumab : Extensive-stage small cell lung cancer – only adults (18 years old or older)
Epirubicin : Small cell lung cancer – only adults (18 years old or older)
Etoposide : Small cell lung cancer (SCLC) – only adults (18 years old or older)
Tarlatamab : Extensive stage small cell lung cancer – only adults (18 years old or older)
Smallpox
Smallpox, live attenuated : Active immunisation against smallpox – only adults (18 years old or older)
Tecovirimat : Smallpox, monkeypox, cowpox – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Smoking cessation drug therapy
Bupropion : Smoking cessation in nicotine-dependent patients – only adults (18 years old or older)
Nicotine : Tobacco dependence, nicotine withdrawal symptoms, smoking cessation – only adults (18 years old or older)
Varenicline : Smoking cessation – only adults (18 years old or older)
Smoking cessation therapy
Nicotine : Tobacco dependence, nicotine withdrawal symptoms, smoking cessation – only adults (18 years old or older)
Social phobia
Escitalopram : Social anxiety disorder – only adults (18 - 65 years old)
Moclobemide : Social phobia – only adults (18 years old or older)
Paroxetine : Social anxiety disorders (social phobia) – only adults (18 years old or older)
Sertraline : Social anxiety disorder – only adults (18 years old or older)
Venlafaxine : Social Anxiety Disorder (Social Phobia) – only adults (18 years old or older)
Solar degeneration
Hydroxychloroquine : Rheumatoid arthritis, discoid and systemic lupus erythematosus, sunlight damaged skin – only adults (18 years old or older)
Solar erythema
Chlorhexidine : Burns, scalds, scratches, cuts, abrasions, sunburn blisters, infected cracked skin – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Solar keratosis
Diclofenac : Actinic keratosis – only adults (18 years old or older)
Fluorouracil : Pre-malignant and malignant skin lesions – only adults (18 years old or older)
Imiquimod : Actinic keratosis – only adults (18 years old or older)
Tirbanibulin : Actinic keratosis – only adults (18 years old or older)
Solid tumour with neurotrophic receptor tyrosine kinase
Entrectinib : Solid tumours expressing a neurotrophic tyrosine receptor kinase (NTRK) gene fusion – only minors (0 - 18 years old) , adults (18 years old or older)
Larotrectinib : Solid tumours that display a Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Larotrectinib : Solid tumours that display a Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion – only adults (18 - 65 years old)
Repotrectinib : Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion-positive solid tumors – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Sore mouth
Dichlorobenzyl alcohol : Sore mouth – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Spasm
Chlordiazepoxide : Muscle spasm – only elderly (65 years old or older)
Chlordiazepoxide : Muscle spasm – only adults (18 - 65 years old)
Diazepam : Muscle spasm – only elderly (65 years old or older)
Diazepam : Muscle spasm – only adults (18 - 65 years old)
Spasm of back muscles
Thiocolchicoside : Painful muscle spasms in acute spinal pathology – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Spasm of bladder
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only children (1 year - 12 years old)
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Spasm of cervix uteri
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only children (1 year - 12 years old)
Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Spasmodic movement
Primidone : Grand mal and psychomotor (temporal lobe) epilepsy, focal or Jacksonian seizures, myoclonic jerks, akinetic attacks – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Spasmodic rhinorrhea
Azelastine : Seasonal allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Budesonide : Seasonal and perennial allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Cetirizine : Seasonal and perennial allergic rhinitis, chronic idiopathic urticaria – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema
Fexofenadine : Seasonal allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Methylprednisolone : Seasonal allergic rhinitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Methylprednisolone : Seasonal allergic rhinitis – only adults (18 years old or older)
Mizolastine : Seasonal allergic rhinoconjunctivitis (hay fever), perennial allergic rhinoconjunctivitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Mometasone : Seasonal allergic rhinitis – only children (1 year - 12 years old)
Mometasone : Seasonal allergic rhinitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Triamcinolone : Seasonal allergic rhinitis – only adults (18 years old or older)
Spasmodic torticollis
Botulinum toxin type A : Idiopathic cervical dystonia (spasmodic torticollis) – only adults (18 years old or older)
Botulinum toxin type B : Cervical dystonia (torticollis) – only adults (18 years old or older)
Spinal block
Chloroprocaine : Spinal anaesthesia in planned surgical procedure not exceeding 40 minutes – only adults (18 - 65 years old)
Levobupivacaine : Intrathecal anaesthesia – only adults (18 years old or older)
Spinal cord compression
Zoledronic acid : Prevention of skeletal related events – only adults (18 years old or older)
Spinal muscular atrophy
Nusinersen : Spinal muscular atrophy 5q – only adults (18 - 65 years old)
Risdiplam : 5q spinal muscular atrophy (SMA) – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Spiral computed tomography scan
Iopromide : Spiral computed tomography scan – only adults (18 - 65 years old)
Sprain of ligament
Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Ibuprofen : Muscular pain, sprains, strains, sports injuries – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Nimesulide : Sprain – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Squamous cell carcinoma of anogenital area
Bleomycin : Squamous cell carcinoma (SCC) of the head and neck, cervix, external genitalia – only adults (18 years old or older)
Squamous cell carcinoma of cervix
Bleomycin : Squamous cell carcinoma (SCC) of the head and neck, cervix, external genitalia – only adults (18 years old or older)
Squamous cell carcinoma of head and neck
Bleomycin : Squamous cell carcinoma (SCC) of the head and neck, cervix, external genitalia – only adults (18 years old or older)
Cetuximab : Squamous cell cancer of the head and neck – only adults (18 years old or older)
Cis-Diaminedichloroplatinum : Head and neck squamous-cell epithelioma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Docetaxel : Squamous cell carcinoma of the head and neck – only adults (18 years old or older)
Fluorouracil : Squamous cell carcinoma of the head and neck – only adults (18 years old or older)
Nivolumab : Squamous cell cancer of the head and neck – only adults (18 years old or older)
Pembrolizumab : First-line treatment of metastatic or unresectable recurrent head and neck squamous cell carcinoma with PD-L1 with a CPS ≥1 – only adults (18 years old or older)
Pembrolizumab : Recurrent or metastatic head and neck squamous cell carcinoma with PD-L1 with a ≥50% TPS – only adults (18 years old or older)
Temoporfin : Head and neck squamous cell carcinoma – only adults (18 years old or older)
Squamous cell carcinoma of skin
Cemiplimab : Metastatic or locally advanced cutaneous squamous cell carcinoma – only adults (18 years old or older)
Squamous non-small cell lung cancer
Afatinib : Non-small cell lung cancer (NSCLC) of squamous histology – only adults (18 years old or older)
Pembrolizumab : First-line treatment of metastatic squamous non-small cell lung carcinoma – only adults (18 years old or older)
Stable angina
Amlodipine : Chronic stable angina pectoris, vasospastic angina – only adults (18 years old or older)
Carvedilol : Chronic stable angina pectoris – only adults (18 years old or older)
Felodipine : Stable angina pectoris – only adults (18 years old or older)
Ivabradine : Chronic stable angina pectoris – only adults (18 years old or older)
Nicorandil : Stable angina pectoris – only adults (18 years old or older)
Ranolazine : Stable angina pectoris – only adults (18 years old or older)
Trimetazidine : Stable angina pectoris – only adults (18 years old or older)
Staphylococcal infectious disease
Rifampicin : Staphylococcal infection – only adults (18 years old or older)
Status epilepticus
Diazepam : Status epilepticus – only elderly (65 years old or older)
Diazepam : Status epilepticus – only adults (18 - 65 years old)
Lorazepam : Status epilepticus – only elderly (65 years old or older)
Lorazepam : Status epilepticus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Lorazepam : Status epilepticus – only adults (18 - 65 years old)
Phenytoin : Status epilepticus, severe head injury – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Stevens-Johnson syndrome
Methylprednisolone : Stevens-Johnson syndrome – only minors (0 - 18 years old)
Methylprednisolone : Stevens-Johnson syndrome – only adults (18 years old or older)
Stokes-Adams attack
Isoprenaline : Stokes-Adams attack – only adults (18 years old or older)
Stomach ache
Hydrotalcite : Stomach ache – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Magnesium hydroxide : Stomach discomfort, indigestion, hyperacidity, heartburn, flatulence – only children (1 year - 12 years old)
Magnesium hydroxide : Stomach discomfort, indigestion, hyperacidity, heartburn, flatulence – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Paracetamol : Pain, fever – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Stomatitis
Benzydamine : Painful oropharyngeal conditions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ketoprofen : Irritating and inflammatory conditions of the oral cavity – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Strain
Diethylamine salicylate : Lumbago, fibrositis, sciatica, bruises, strains – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Ibuprofen : Muscular pain, sprains, strains, sports injuries – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Ketoprofen : Painful musculoskeletal conditions caused by trauma, pain of non serious arthritis – only adults (18 years old or older)
Streptococcal infectious disease
Tetracycline : Streptococcal infections – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Streptococcal sore throat
Clarithromycin : Streptococcal pharyngitis and tonsillitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Streptococcal tonsillitis
Clarithromycin : Streptococcal pharyngitis and tonsillitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Stress bladder incontinence
Duloxetine : Moderate to severe Stress Urinary Incontinence (SUI) – only adults (18 years old or older)
Stress echocardiography using dobutamine
Dobutamine : Dobutamine stress echocardiography – only adults (18 years old or older)
Subacute idiopathic demyelinating polyradiculoneuropathy
Prednisolone : Subacute inflammatory demyelinating polyradiculoneuropathy – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Subacute neuronopathic Gaucher's disease
Imiglucerase : Non-neuronopathic (Type 1) Gaucher disease, chronic neuronopathic (Type 3) Gaucher disease – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Subsequent non-ST segment elevation myocardial infarction
Bivalirudin : Treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction – only adults (18 years old or older)
Superficial basal cell carcinoma
Fluorouracil : Pre-malignant and malignant skin lesions – only adults (18 years old or older)
Imiquimod : Superficial basal cell carcinoma – only adults (18 years old or older)
Superficial mycosis
Isoconazole : Superficial fungal infections of the skin – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Superovulation
Choriogonadotropin alpha : Follicular maturation and luteinisation – women, only adults (18 - 65 years old)
Chorionic gonadotrophin (human) : Promotion of controlled superovulation – women, only adults (18 - 65 years old)
Suppressed lactation
Cabergoline : Suppression of physiological lactation – women, only adults (18 - 65 years old)
Supraventricular arrhythmia
Antazoline : Paroxysmal arrhythmias of supraventricular origin – only adults (18 years old or older)
Flecainide : Supraventricular arrhythmia, re-entrant atrioventricular node tachycardia, Wolff-Parkinson-White pattern – only elderly (65 years old or older)
Flecainide : Supraventricular arrhythmia, re-entrant atrioventricular node tachycardia, Wolff-Parkinson-White pattern – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Supraventricular tachycardia
Amiodarone : Tachyarrhythmias – only adults (18 years old or older)
Esmolol : Supraventricular tachycardia – only adults (18 years old or older)
Landiolol : Supraventricular tachycardia – only adults (18 years old or older)
Metoprolol : Supraventricular tachycardia – only adults (18 years old or older)
Oxprenolol : Supraventricular tachycardia, atrial fibrillation, ventricular tachycardia – only adults (18 years old or older)
Verapamil : Supraventricular tachycardias – only minors (0 - 18 years old) , adults (18 years old or older)
Verapamil : Supraventricular tachycardias – only minors (0 - 18 years old) , adults (18 years old or older)
Surgical procedure
Floxacillin : Prophylactic agent during major surgical procedures – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Surgical procedure on eye proper
Acetylcholine : To obtain rapid and complete miosis – only adults (18 years old or older)
Surgical procedure on eye region
Bromfenac : Postoperative ocular inflammation following cataract extraction – only adults (18 years old or older)
Surgical procedure on primary malignant neoplasm of breast
Pegulicianine : Imaging of breast cancer – only adults (18 years old or older)
Swimmer's ear
Clobetasone : Otitis externa, prurigo nodularis, insect bite reactions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Erythromycin : Ear infection – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Hydrocortisone : Prurigo nodularis, neurodermatoses, otitis externa, intertrigo, napkin rash – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Swollen abdomen
Itopride : Functional, non-ulcer dyspepsia, bloating, gastric fullness, discomfort to pain in epigastrium, anorexia, heartburn, nausea – only adults (18 years old or older)
Symptomatic congestive heart failure
Enalapril : Symptomatic congestive heart failure – only adults (18 years old or older)
Perindopril : Symptomatic heart failure – only adults (18 years old or older)
Ramipril : Symptomatic heart failure – only adults (18 years old or older)
Synovitis
Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older)
Prednisolone : Synovitis – only adults (18 years old or older)
Triamcinolone : Rheumatoid arthritis, juvenile idiopathic arthritis, osteoarthritis, post-traumatic arthritis, synovitis, tendinitis, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Syphilis
Ceftriaxone : Syphilis – only newborns (0 - 40 days old)
Ceftriaxone : Syphilis – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Ceftriaxone : Syphilis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Syphilitic gumma
Tetracycline : Syphilis of more than one year's duration – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Systemic infection
Ulinastatin : Severe sepsis – only adults (18 years old or older)
Systemic lupus erythematosus
Anifrolumab : Moderate to severe, active autoantibody-positive systemic lupus erythematosus (SLE) – only adults (18 years old or older)
Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Belimumab : Systemic lupus erythematosus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Hydroxychloroquine : Juvenile idiopathic arthritis, discoid and systemic lupus erythematosus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Hydroxychloroquine : Rheumatoid arthritis, discoid and systemic lupus erythematosus, sunlight damaged skin – only adults (18 years old or older)
Methylprednisolone : Systemic lupus erythematosus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Prednisolone : Systemic lupus erythematosus – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Systemic mastocytosis with associated clonal haematological non-mast cell lineage disease
Midostaurin : Aggressive systemic mastocytosis, systemic mastocytosis with associated haematological neoplasm, mast cell leukaemia – only adults (18 - 65 years old)
Systemic onset juvenile chronic arthritis
Anakinra : Still's Disease – only adults (18 years old or older)
Canacinumab : Still's disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Tocilizumab : Systemic juvenile idiopathic arthritis (sJIA) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Systemic sclerosis
Bosentan : Systemic sclerosis – only adults (18 years old or older)

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