Indications A-Z

RxReasoner presents a comprehensive list of pharmaceutical treatment indications drawn from medicine package inserts issued by authoritative regulatory bodies globally.

This index serves as a valuable tool to quickly access information on the recommended therapeutic approaches for different medical conditions, diseases or symptoms.

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Indications starting with 'A'

Indication	Treatments
Abdominal aortogram	Iopromide : Abdominal aortogram – only adults (18 - 65 years old)
Abdominal wind pain	Sodium bicarbonate : Wind pain, griping pain – only infants (40 days - 1 year old)
Abnormal height in relation to growth / age standard	Somatropin : Growth disturbance in short children born small for gestational age – only minors (0 - 18 years old)
Abrasion	Cetrimide : Minor burns, napkin rash, abrasions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Chlorhexidine : Burns, scalds, scratches, cuts, abrasions, sunburn blisters, infected cracked skin – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Abscess	Gentamicin : Abscess – only newborns (0 - 40 days old) Gentamicin : Abscess – only infants (40 days - 1 year old) Gentamicin : Abscess – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Achondroplasia	Vosoritide : Achondroplasia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Acne	Adapalene : Acne vulgaris – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Azelaic acid : Acne vulgaris – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Benzoyl peroxide : Moderate acne vulgaris – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Doxycycline : Acne vulgaris – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Erythromycin : Acne vulgaris – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Isotretinoin : Acne – only adolescents (12 years - 18 years old) , adults (18 years old or older) Tretinoin : Acne vulgaris – only adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Acne rosacea, erythematous telangiectatic type	Brimonidine : Facial erythema of rosacea – only adults (18 years old or older)
Acne rosacea, papular type	Methronidazole : Inflammatory papulo-pustules rosacea – only adults (18 years old or older)
Acne vulgaris	Tetracycline : Acne vulgaris – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Acquired aplastic anemia	Eltrombopag : Acquired severe aplastic anaemia (SAA) – only adults (18 years old or older)
Acquired hemophilia	Susoctocog alfa : Acquired haemophilia caused by antibodies to Factor VIII – only adults (18 - 65 years old)
Acquired hypothyroidism	Levothyroxine : Acquired hypothyroidism – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Acquired thrombotic thrombocytopenic purpura	Caplacizumab : Acquired thrombotic thrombocytopenic purpura (aTTP) – only adults (18 - 65 years old)
Acrocyanosis	Naftidrofuryl : Peripheral vascular disorders – only adults (18 years old or older)
Acromegaly	Bromocriptine : Acromegaly – only adults (18 - 65 years old) Lanreotide : Acromegaly – only adults (18 years old or older) Octreotide : Acromegaly – only adults (18 years old or older) Pasireotide : Acromegaly – only adults (18 years old or older) Pegvisomant : Acromegaly – only adults (18 - 65 years old)
Actinomycotic infection	Benzylpenicillin : Actinomycosis – only newborns (0 - 40 days old) Benzylpenicillin : Actinomycosis – only infants (40 days - 1 year old) , children (1 year - 12 years old) Benzylpenicillin : Actinomycosis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute adrenal failure	Betamethasone : Acute adrenal crisis – only infants (40 days - 1 year old) , children (1 year - 12 years old) Betamethasone : Acute adrenal crisis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Hydrocortisone : Acute adrenal insufficiency – only adolescents (12 years - 18 years old) , adults (18 years old or older) Hydrocortisone : Acute adrenal insufficiency – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old)
Acute allergic reaction	Antazoline : Acute allergic conditions – only adolescents (12 years - 18 years old) , adults (18 years old or older) Betamethasone : Status asthmaticus, acute allergic reactions – only children (1 year - 12 years old) Betamethasone : Status asthmaticus, acute allergic reactions – only adolescents (12 years - 18 years old) , adults (18 years old or older) Hydrocortisone : Status asthmaticus, acute allergic reaction – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old) Hydrocortisone : Status asthmaticus, acute allergic reaction – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute amebic rectocolitis	Doxycycline : Acute intestinal amoebiasis – only children (1 year - 12 years old) Doxycycline : Acute intestinal amoebiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute angle-closure glaucoma	Acetazolamide : Secondary or acute narrow angle glaucoma – only adults (18 years old or older)
Acute atopic conjunctivitis	Dexamethasone : Acute atopic conjunctivitis – only adults (18 years old or older)
Acute bacterial sinusitis	Moxifloxacin : Acute bacterial sinusitis – only adults (18 years old or older)
Acute bronchiolitis caused by respiratory syncytial virus	Nirsevimab : Respiratory Syncytial Virus (RSV) lower respiratory tract disease – only newborns (0 - 40 days old) , infants (40 days - 1 year old)
Acute coronary insufficiency	Glyceryl trinitrate : Acute coronary insufficiency – only adults (18 years old or older)
Acute coronary syndrome	Bivalirudin : Treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction – only adults (18 years old or older) Clopidogrel : Acute coronary syndrome – only adults (18 years old or older) Enoxaparin : Acute coronary syndrome – only elderly (65 years old or older) Enoxaparin : Acute coronary syndrome – only adults (18 - 65 years old)
Acute diarrhoea	Loperamide : Acute diarrhoea – only adolescents (12 years - 18 years old) , adults (18 years old or older) Racecadotril : Acute diarrhoea – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Acute exacerbation of chronic bronchitis	Moxifloxacin : Acute exacerbation of chronic bronchitis – only adults (18 years old or older) Prulifloxacin : Acute exacerbation of chronic bronchitis – only adults (18 years old or older)
Acute exacerbation of chronic congestive heart failure	Levosimendan : Acutely decompensated chronic heart failure (ADHF) – only adults (18 years old or older)
Acute exacerbation of chronic schizophrenia	Levosulpiride : Acute schizophrenia – only adults (18 years old or older)
Acute febrile mucocutaneous lymph node syndrome	Immunoglobulins, normal human, IV : Kawasaki disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute gout	Etoricoxib : Acute gouty arthritis – only adults (18 years old or older) Indometacin : Acute gouty arthritis – only adults (18 years old or older) Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older)
Acute infective cystitis	Norfloxacin : Acute infective cystitis – only adults (18 years old or older)
Acute interstitial nephritis	Prednisolone : Acute interstitial nephritis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute leukemia	Methotrexate : Acute leukemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute lymphoid leukemia	22-Oxovincaleukoblastine : Acute lymphocytic leukaemia, chronic lymphocytic leukaemia, acute myelogenous leukaemia, chronic myelogenous leukaemia – only adults (18 years old or older) Asparaginase : Acute lymphoblastic leukaemia (ALL) – only infants (40 days - 1 year old) Asparaginase : Acute lymphoblastic leukaemia (ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Clofarabine : Acute lymphoblastic leukaemia (ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Cyclophosphamide : Acute Lymphocytic Leukemia (ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Cytarabine : Acute myeloid leukaemia, acute non-lymphoblastic leukaemia, acute lymphoblastic leukaemia, acute lymphocytic leukaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Daunorubicin : Acute lymphocytic leukaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Idarubicin : Acute lymphoblastic leukaemia (ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Idarubicin : Acute lymphoblastic leukaemia (ALL) – only adults (18 years old or older) Mercaptopurine : Acute lymphoblastic leukaemia (ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Acute lymphoid leukemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Pegaspargase : Acute lymphoblastic leukaemia (ALL) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Pegaspargase : Acute lymphoblastic leukaemia (ALL) – only adults (18 - 65 years old)
Acute myeloid leukemia	22-Oxovincaleukoblastine : Acute lymphocytic leukaemia, chronic lymphocytic leukaemia, acute myelogenous leukaemia, chronic myelogenous leukaemia – only adults (18 years old or older) Azacitidine : Myelodysplastic syndromes, chronic myelomonocytic leukaemia, acute myeloid leukaemia – only adults (18 years old or older) Cytarabine : Acute myeloid leukaemia, acute non-lymphoblastic leukaemia, acute lymphoblastic leukaemia, acute lymphocytic leukaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Daunorubicin : Acute lymphocytic leukaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Decitabine : Acute myeloid leukaemia – only adults (18 years old or older) Etoposide : Acute myeloid leukaemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Etoposide : Acute myeloid leukaemia – only adults (18 years old or older) Gilteritinib : Ρelapsed or refractory acute myeloid leukaemia with a FLT3 mutation – only adults (18 years old or older) Glasdegib : Acute myeloid leukaemia (AML) – only adults (18 - 65 years old) Idarubicin : Acute myeloid leukaemia (AML) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Idarubicin : Acute myeloid leukaemia (AML) – only adults (18 years old or older) Ivosidenib : Acute myeloid leukaemia with an isocitrate dehydrogenase-1 R132 mutation – only adults (18 years old or older) Mitoxantrone : Acute myeloid leukaemia (AML) – only adults (18 - 65 years old) Quizartinib : Acute myeloid leukaemia that is FLT3-ITD positive – only adults (18 years old or older)
Acute myeloid leukemia in remission	Histamine : Acute myeloid leukaemia (AML) in first remission concomitantly treated with interleukin-2 (IL-2) – only adults (18 - 65 years old)
Acute myeloid leukemia with FMS-like tyrosine kinase-3 mutation	Midostaurin : Acute myeloid leukemia with FMS-like tyrosine kinase-3 mutation – only adults (18 - 65 years old)
Acute myocardial infarction	Acetylsalicylic acid : Acute myocardial infarction – only adults (18 years old or older) Alteplase : Acute myocardial infarction – only adults (18 years old or older) Bivalirudin : Treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction – only adults (18 years old or older) Lisinopril : Acute myocardial infarction – only adults (18 years old or older) Metoprolol : Acute myocardial infarction – only adults (18 years old or older) Ramipril : Secondary prevention after acute myocardial infarction – only adults (18 years old or older)
Acute non-ST segment elevation myocardial infarction	Bivalirudin : Treatment of adult patients with unstable angina/non-ST segment elevation myocardial infarction – only adults (18 years old or older)
Acute pain	Bupivacaine : Acute pain – only adolescents (12 years - 18 years old) , adults (18 years old or older) Bupivacaine : Acute pain – only children (1 year - 12 years old) Etoricoxib : Acute pain conditions – only adults (18 years old or older) Nimesulide : Acute pain – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute pancreatitis	Ulinastatin : Mild and severe acute pancreatitis – only adults (18 years old or older)
Acute peptic ulcer with hemorrhage	Cimetidine : Prophylaxis of gastrointestinal haemorrhage from stress ulceration – only adults (18 years old or older)
Acute pre B-cell lymphoblastic leukemia	Brexucabtagene autoleucel : Precursor B-cell acute lymphoblastic leukemia – only adults (18 years old or older)
Acute promyelocytic leukaemia (clinical)	Arsenic trioxide : Acute promyelocytic leukaemia – only adults (18 years old or older) Tretinoin : Acute promyelocytic leukaemia (APL) – only adults (18 - 65 years old)
Acute relapsing multiple sclerosis	Glatiramer : Relapsing forms of multiple sclerosis (MS) – only adults (18 - 65 years old) Methylprednisolone : Acute exacerbations of multiple sclerosis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Methylprednisolone : Acute exacerbations of multiple sclerosis – only adults (18 years old or older) Ublituximab : Relapsing forms of multiple sclerosis – only adults (18 years old or older)
Acute renal failure with oliguria	Mannitol : Oliguric phase of acute renal failure – only children (1 year - 12 years old) Mannitol : Oliguric phase of acute renal failure – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute rheumatic fever with valvulitis	Prednisolone : Acute rheumatic fever with valvulitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute rhinosinusitis	Prulifloxacin : Acute rhinosinusitis – only adults (18 years old or older)
Acute severe refractory exacerbation of asthma	Aminophylline : Pulmonary oedema, paroxysmal nocturnal dyspnoea, status asthmaticus, acute bronchospasm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Betamethasone : Status asthmaticus, acute allergic reactions – only children (1 year - 12 years old) Betamethasone : Status asthmaticus, acute allergic reactions – only adolescents (12 years - 18 years old) , adults (18 years old or older) Hydrocortisone : Status asthmaticus, acute allergic reaction – only newborns (0 - 40 days old) , infants (40 days - 1 year old) , children (1 year - 12 years old) Hydrocortisone : Status asthmaticus, acute allergic reaction – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Acute ST segment elevation myocardial infarction	Reteplase : Myocardial infarction – only adults (18 years old or older)
Acute thrombosis of superficial vein of lower limb	Fondaparinux : Acute symptomatic spontaneous superficial-vein thrombosis of the lower limbs – only adults (18 years old or older)
Adenocarcinoma of prostate	Padeliporfin : Adenocarcinoma of the prostate – men, only adults (18 years old or older)
Adenocarcinoma of stomach	Docetaxel : Gastric adenocarcinoma, adenocarcinoma of the gastroesophageal junction – only adults (18 years old or older) Nivolumab : Gastric, gastro-oesophageal junction or oesophageal adenocarcinoma – only adults (18 years old or older)
Adhesive capsulitis of shoulder	Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Administration of analgesic	Alfentanil : Analgesia, suppression of respiratory activity – only adults (18 - 65 years old) Pethidine : Moderate to severe pain – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Pethidine : Moderate to severe pain – only elderly (65 years old or older) Pethidine : Moderate to severe pain – only adults (18 - 65 years old)
Adrenal cortical hypofunction	Prednisolone : Adrenal insufficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Adrenal Cushing's syndrome	Ketoconazole : Endogenous Cushing's syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Adrenoleukodystrophy	Elivaldogene autotemcel : Early cerebral adrenoleukodystrophy in patients with an ABCD1 genetic mutation – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Adult growth hormone deficiency	Somapacitan : Adult growth hormone deficiency (AGHD) – only adults (18 years old or older)
Adult hepatocellular carcinoma	Durvalumab : Combination therapy of advanced or unresectable hepatocellular carcinoma – only adults (18 years old or older) Durvalumab : Monotherapy of advanced or unresectable hepatocellular carcinoma – only adults (18 years old or older)
Adult onset Still's disease	Anakinra : Still's Disease – only adults (18 years old or older) Canacinumab : Still's disease – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Adult respiratory distress syndrome	Prednisolone : Adult respiratory distress syndrome – only adults (18 years old or older)
AF - Paroxysmal atrial fibrillation	Propafenone : Ventricular arrhythmias, paroxysmal supraventricular tachyarrhythmias – only adults (18 years old or older)
Afibrinogenaemia	Human fibrinogen : Congenital hypofibrinogenaemia, afibrinogenaemia with bleeding tendency – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Age-related cognitive decline	Ginkgo biloba : For the improvement of age-associated cognitive impairment – only adults (18 years old or older)
Aggressive behavior	Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only elderly (65 years old or older) Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only adults (18 - 65 years old) Lithium : Aggressive behaviour, self mutilating behaviour – only adults (18 years old or older)
Aggressive fibromatosis	Nirogacestat : Progressing desmoid tumors – only adults (18 - 65 years old)
Aggressive systemic mastocytosis	Midostaurin : Aggressive systemic mastocytosis, systemic mastocytosis with associated haematological neoplasm, mast cell leukaemia – only adults (18 - 65 years old)
Airway hyperreactivity	Bambuterol : Asthma, bronchospasm, reversible airways obstruction – only adults (18 years old or older) Budesonide : Bronchial asthma – only children (1 year - 12 years old) Budesonide : Bronchial asthma – only adolescents (12 years - 18 years old) , adults (18 years old or older) Ciclesonide : Asthma – only adolescents (12 years - 18 years old) , adults (18 years old or older) Cromoglicic acid : Bronchial asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Dexamethasone : Bronchial asthma – only adults (18 years old or older) Eformoterol : Asthma – only adolescents (12 years - 18 years old) , adults (18 years old or older) Fluticasone : Asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Fluticasone : Asthma – only adults (18 years old or older) Ipratropium : Bronchospasm, asthma, bronchitis – only children (1 year - 12 years old) Ipratropium : Bronchospasm, chronic obstructive pulmonary disease (COPD), asthma, bronchitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Ketotifen : Bronchial asthma, allergic bronchitis, allergic rhinitis, multisystem allergic diseases, allergic skin reactions – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Metaproterenol : Bronchial asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Bronchial asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Methylprednisolone : Bronchial asthma – only adults (18 years old or older) Nedocromil : Bronchial asthma – only adults (18 - 65 years old) Prednisolone : Asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Bronchial asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Prednisolone : Bronchial asthma – only adults (18 years old or older) Salbutamol : Bronchial asthma – only adults (18 years old or older) Salbutamol : Bronchial asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Salmeterol : Asthma – only adolescents (12 years - 18 years old) , adults (18 years old or older) Tiotropium : Asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Airways obstruction reversible	Bambuterol : Asthma, bronchospasm, reversible airways obstruction – only adults (18 years old or older)
Alcohol dependence	Nalmefene : Reduction of alcohol consumption – only adults (18 years old or older) Naltrexone : Alcohol abstinence support – only adults (18 - 65 years old)
Alcohol withdrawal syndrome	Chlordiazepoxide : Acute alcohol withdrawal – only elderly (65 years old or older) Chlordiazepoxide : Acute alcohol withdrawal – only adults (18 - 65 years old) Diazepam : Alcohol withdrawal – only elderly (65 years old or older) Diazepam : Alcohol withdrawal – only adults (18 - 65 years old)
Allergic asthma	Omalizumab : Allergic asthma – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic bronchitis	Ketotifen : Bronchial asthma, allergic bronchitis, allergic rhinitis, multisystem allergic diseases, allergic skin reactions – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic condition	Diphenhydramine : Allergic conditions and reactions – only adolescents (12 years - 18 years old) , adults (18 years old or older) Ketotifen : Allergic conditions – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic conjunctivitis	Bilastine : Allergic rhino-conjunctivitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema Epinastine : Seasonal allergic conjunctivitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Levocabastine : Allergic conjunctivitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic contact dermatitis	Betamethasone : Irritant contact dermatitis, allergic contact dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Allergic contact dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic granulomatosis angiitis	Mepolizumab : Eosinophilic granulomatosis with polyangiitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic reaction	Diphenhydramine : Allergic conditions and reactions – only adolescents (12 years - 18 years old) , adults (18 years old or older) Ketotifen : Bronchial asthma, allergic bronchitis, allergic rhinitis, multisystem allergic diseases, allergic skin reactions – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic rhinitis	Desloratadine : Allergic rhinitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older) Ebastine : Allergic rhinitis (seasonal and perennial) – only adolescents (12 years - 18 years old) , adults (18 years old or older) Fluticasone : Allergic rhinitis – only children (1 year - 12 years old) Fluticasone : Allergic rhinitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Fluticasone furoate : Allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Ketotifen : Bronchial asthma, allergic bronchitis, allergic rhinitis, multisystem allergic diseases, allergic skin reactions – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Levocabastine : Allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Levocetirizine : Allergic rhinitis, urticaria – only children (1 year - 12 years old) Levocetirizine : Allergic rhinitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older) Loratadine : Allergic rhinitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Promethazine : Allergic rhinitis, urticaria, anaphylactic reactions to drugs – only children (1 year - 12 years old) Promethazine : Allergic rhinitis, urticaria, anaphylactic reactions to drugs – only adolescents (12 years - 18 years old) , adults (18 years old or older) Rupatadine : Allergic rhinitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Allergic urticaria	Mizolastine : Seasonal allergic rhinoconjunctivitis (hay fever), perennial allergic rhinoconjunctivitis, urticaria – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Allogeneic peripheral blood stem cell transplant	Treosulfan : Allogeneic haematopoietic stem cell transplantation (alloHSCT) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Treosulfan : Allogeneic haematopoietic stem cell transplantation (alloHSCT) – only adults (18 years old or older)
Alopecia areata	Baricitinib : Alopecia areata – only adults (18 years old or older) Ritlecitinib : Alopecia areata – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Alzheimer's disease	Donanemab : Mild Alzheimer's dementia – only adults (18 years old or older) Donepezil : Mild to moderately severe Alzheimer's dementia – only adults (18 years old or older) Galantamine : Mild to moderately severe dementia of the Alzheimer type – only adults (18 years old or older) Lecanemab : Mild Alzheimer's dementia – only adults (18 years old or older) Memantine : Moderate to severe Alzheimer’s disease – only adults (18 years old or older) Rivastigmine : Mild to moderately severe Alzheimer's dementia – only adults (18 years old or older)
Amebic hepatitis	Chloroquine : Amebic hepatitis – only adults (18 years old or older)
Amebic liver abscess	Tinidazole : Amoebic involvement of the liver – only children (1 year - 12 years old) Tinidazole : Amoebic involvement of the liver – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Amenorrhea	Bromocriptine : Amenorrhoea and oligomenorrhoea, with or without galactorrhoea – women, only adults (18 - 65 years old)
Amoebic dysentery	Tinidazole : Intestinal amoebiasis – only children (1 year - 12 years old) Tinidazole : Intestinal amoebiasis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
AMPE - Acute massive pulmonary embolism	Alteplase : Acute massive pulmonary embolism with haemodynamic instability – only adults (18 years old or older)
Amyloid polyneuropathy type I	Vutrisiran : Hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis) with stage 1 or stage 2 polyneuropathy – only adults (18 years old or older)
Amyotrophic lateral sclerosis	Riluzole : Amyotrophic lateral sclerosis (ALS) – only adults (18 years old or older) Tofersen : Amyotrophic lateral sclerosis with a mutation in the superoxide dismutase 1 gene – only adults (18 years old or older)
Anal fissure	Cinchocaine : Hemorrhoids, anal fissure, pruritus ani – only adults (18 years old or older)
Anal spasm	Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only children (1 year - 12 years old) Butylscopolamine : Spasm, endoscopy of the genito-urinary tract or gastro- intestinal tract, Irritable Bowel Syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Analgesia for labour/delivery	Levobupivacaine : Labour analgesia – women, only adults (18 - 65 years old)
Anancastic neurosis	Escitalopram : Obsessive-compulsive disorder – only adults (18 - 65 years old) Fluoxetine : Obsessive-compulsive disorder – only adults (18 years old or older) Fluvoxamine : Obsessive Compulsive Disorder (OCD) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Fluvoxamine : Obsessive Compulsive Disorder (OCD) – only adults (18 years old or older) Paroxetine : Obsessive compulsive disorder – only adults (18 years old or older) Sertraline : Obsessive compulsive disorder (OCD) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Anaphylaxis	Dexamethasone : Anaphylaxis – only adults (18 years old or older) Epinephrine : Acute anaphylaxis – only adults (18 years old or older) Hydrocortisone : Anaphylaxis – only minors (0 - 18 years old) , adults (18 years old or older) Methylprednisolone : Anaphylaxis – only adults (18 years old or older) Methylprednisolone : Anaphylaxis – only minors (0 - 18 years old) Prednisolone : Anaphylaxis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Anaphylaxis – only adults (18 years old or older)
Anaplastic large T-cell systemic malignant lymphoma	Brentuximab vedotin : Systemic anaplastic large cell lymphoma (sALCL) – only adults (18 years old or older)
Anaplastic lymphoma kinase negative non-small cell lung cancer	Atezolizumab : Early-stage non-small cell lung cancer, EGFR and ALK-negative – only adults (18 years old or older)
Anaplastic lymphoma kinase-positive non-small cell lung cancer	Alectinib : Anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) – only adults (18 years old or older) Brigatinib : Anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) – only adults (18 years old or older) Crizotinib : First-line treatment of ALK-positive non-small cell lung cancer – only adults (18 years old or older) Lorlatinib : Non-small cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK)-positive – only adults (18 - 65 years old)
Anemia	Epoetin alfa : Anaemia with risk of primary myelodysplastic syndromes (MDS) who have low serum erythropoietin – only adults (18 years old or older) Epoetin zeta : Anaemia with risk of primary myelodysplastic syndromes (MDS) who have low serum erythropoietin – only adults (18 years old or older)
Anemia co-occurrent and due to chronic kidney disease	Darbepoetin alfa : Anaemia associated with chronic renal failure (CRF) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Darbepoetin alfa : Anaemia associated with chronic renal failure (CRF) – only adults (18 years old or older) Epoetin alfa : Anaemia associated with chronic renal failure (CRF) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Epoetin alfa : Anaemia associated with chronic renal failure (CRF) – only adults (18 years old or older) Epoetin beta : Anaemia associated with chronic kidney disease (CKD) – only adults (18 years old or older) Epoetin zeta : Anaemia associated with chronic renal failure (CRF) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Epoetin zeta : Anaemia associated with chronic renal failure (CRF) – only adults (18 years old or older) Roxadustat : Symptomatic anaemia associated with chronic kidney disease (CKD) – only adults (18 years old or older) Vadadustat : Symptomatic anaemia associated with chronic kidney disease – only adults (18 years old or older)
Anemia due to and following chemotherapy	Darbepoetin alfa : Anaemia associated with chemotherapy – only adults (18 years old or older) Epoetin alfa : Anaemia associated with chemotherapy – only adults (18 years old or older) Epoetin zeta : Anaemia associated with chemotherapy – only adults (18 years old or older)
Anemia of chronic renal failure	Epoetin theta : Symptomatic anaemia associated with chronic renal failure – only adults (18 years old or older)
Anesthesia for cesarean section	Bupivacaine : Lumbar epidural anaesthesia for caesarean section – women, only adults (18 - 65 years old) Levobupivacaine : Epidural anaesthesia for caesarean section – women, only adults (18 - 65 years old)
Anesthesia for intrathoracic procedure	Remifentanil : Cardiac anaesthesia – only adults (18 years old or older)
Angina	Acetylsalicylic acid : Stable and unstable angina pectoris – only adults (18 years old or older) Atenolol : Angina pectoris – only adults (18 years old or older) Bisoprolol : Angina pectoris – only adults (18 years old or older) Diltiazem : Angina pectoris – only elderly (65 years old or older) Diltiazem : Angina pectoris – only adults (18 - 65 years old) Glyceryl trinitrate : Angina pectoris – only adults (18 years old or older) Isosorbide dinitrate : Angina pectoris – only adults (18 years old or older) Isosorbide dinitrate : Prophylaxis of angina pectoris – only adults (18 years old or older) Metoprolol : Angina pectoris – only adults (18 years old or older) Oxprenolol : Angina pectoris – only adults (18 years old or older) Pindolol : Prophylactic treatment of angina pectoris – only adults (18 years old or older) Propranolol : Angina pectoris – only adolescents (12 years - 18 years old) , adults (18 years old or older) Verapamil : Angina pectoris – only adults (18 years old or older) Verapamil : Angina pectoris – only adults (18 years old or older)
Angiocardiography	Iodixanol : Cardioangiography – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Iopromide : Angiocardiography – only adults (18 - 65 years old)
Angiocardiography of left heart	Iodixanol : Cardioangiography of left ventricle and aortic root – only adults (18 years old or older)
Angioedema	Chlorphenamine : Hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy – only children (1 year - 12 years old) , elderly (65 years old or older) Chlorphenamine : Hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema Hydrocortisone : Angioneurotic oedema – only minors (0 - 18 years old) , adults (18 years old or older) Methylprednisolone : Angioneurotic oedema – only adults (18 years old or older) Methylprednisolone : Angioneurotic oedema – only minors (0 - 18 years old) Prednisolone : Angioneurotic oedema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Angiofollicular lymph node hyperplasia	Siltuximab : Multicentric Castleman's disease (MCD) – only adults (18 years old or older)
Ankylosing spondylitis	Aceclofenac : Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis – only adults (18 years old or older) Celecoxib : Ankylosing spondylitis – only adults (18 years old or older) Etanercept : Ankylosing spondylitis – only adults (18 years old or older) Etofenamate : Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, folliculitis, periarthritis Etoricoxib : Ankylosing spondylitis – only adults (18 years old or older) Flurbiprofen : Rheumatoid disease, osteoarthritis, ankylosing spondylitis, musculoskeletal disorders, periarthritis, frozen shoulder, bursitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Indometacin : Ankylosing spondylitis – only adults (18 years old or older) Infliximab : Ankylosing spondylitis – only adults (18 years old or older) Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older) Meloxicam : Ankylosing spondylitis – only elderly (65 years old or older) Meloxicam : Ankylosing spondylitis – only adults (18 - 65 years old) Methylprednisolone : Ankylosing spondylitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Naproxen : Rheumatic arthritis, osteoarthritis, ankylosing spondylitis – only adults (18 years old or older) Oxaprozin : Rheumatoid arthritis, ankylosing spondylitis – only adults (18 years old or older) Piroxicam : Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis – only adults (18 years old or older) Secukinumab : Ankylosing spondylitis (AS, radiographic axial spondyloarthritis) – only adults (18 years old or older)
Anovular menstruation	Medroxyprogesterone : Dysfunctional (anovulatory) uterine bleeding – only adults (18 - 65 years old) Norethisterone : Dysfunctional uterine bleeding, polymenorrhoea, menorrhagia, dysmenorrhoea, metropathia haemorrhagia – women, only adults (18 - 65 years old)
Anovulation	Choriogonadotropin alpha : Anovulation, oligo-ovulation – women, only adults (18 - 65 years old) Follitropin alfa : Anovulation – women, only adults (18 - 65 years old)
Anterior uveitis	Dexamethasone : Anterior uveitis – only adults (18 years old or older) Flurbiprofen : Inhibition of intraoperative miosis, post-operative trabeculoplasty inflammation in the anterior segment of the eye – only adults (18 years old or older) Methylprednisolone : Anterior uveitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Anthrax	Benzylpenicillin : Anthrax – only newborns (0 - 40 days old) Benzylpenicillin : Anthrax – only infants (40 days - 1 year old) , children (1 year - 12 years old) Benzylpenicillin : Anthrax – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Anticoagulant prophylaxis	Dalteparin : Prophylaxis of venous thromboembolism in medical patients – only adults (18 years old or older)
Antimalarial prophylaxis	Mefloquine : Malaria chemoprophylaxis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Anxiety	Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only elderly (65 years old or older) Chlorpromazine : Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour – only adults (18 - 65 years old) Clobazam : Anxiety – only adults (18 years old or older) Hydroxyzine : Anxiety – only adults (18 - 65 years old) Hydroxyzine : Anxiety – only elderly (65 years old or older) Meprobamate : Anxiety – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prazepam : Anxiety – only adults (18 years old or older)
Anxiety disorder	Alprazolam : Moderate or severe anxiety, anxiety associated with depression – only elderly (65 years old or older) Alprazolam : Moderate or severe anxiety, anxiety associated with depression – only adults (18 - 65 years old) Bromazepam : Anxiety – only adolescents (12 years - 18 years old) , adults (18 years old or older) Buspirone : Anxiety disorders – only adults (18 years old or older) Chlordiazepoxide : Anxiety – only elderly (65 years old or older) Chlordiazepoxide : Anxiety – only adults (18 - 65 years old) Clobazam : Anxiety – only adults (18 years old or older) Clomipramine : Obsessional and phobic states – only adults (18 years old or older) Diazepam : Anxiety states – only elderly (65 years old or older) Diazepam : Anxiety states – only adults (18 - 65 years old) Mexazolam : Anxiety disorder – only adults (18 years old or older)
Aortic root arteriogram	Iodixanol : Cardioangiography of left ventricle and aortic root – only adults (18 years old or older)
Aortography	Iodixanol : Aortography – only adults (18 years old or older)
Aphthous ulceration of skin and/or mucous membrane	Chlorhexidine : Gingivitis, oral surgery, aphthous ulceration, oral candidal infections – only adolescents (12 years - 18 years old) , adults (18 years old or older) Hexetidine : Mouth infections, gingivitis, sore throat, aphthous ulcer, halitosis, dental surgery – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Aplastic anaemia	Nandrolone : Aplastic anemia – only adults (18 years old or older)
Arginase deficiency	Pegzilarginase : Arginase 1 deficiency – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Arrhythmia	Atenolol : Cardiac arrhythmias – only adults (18 years old or older) Propranolol : Arrhythmias – only children (1 year - 12 years old) Propranolol : Arrhythmias – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Arsenical keratosis	Fluorouracil : Pre-malignant and malignant skin lesions – only adults (18 years old or older)
Arteriography	Iodixanol : Selective visceral arteriography, intra-arterial digital subtraction angiography – only adults (18 years old or older)
Arteriography of cerebral arteries	Iodixanol : Selective cerebral arteriography – only adults (18 years old or older)
Arteriosclerotic vascular disease	Alirocumab : Established atherosclerotic cardiovascular disease – only adults (18 years old or older) Bempedoic acid : Established atherosclerotic cardiovascular disease – only adults (18 years old or older)
Arthritis	Ketoprofen : Painful musculoskeletal conditions caused by trauma, pain of non serious arthritis – only adults (18 years old or older)
Arthrography using contrast	Iopromide : Arthrography using contrast – only adults (18 - 65 years old)
Articular cartilage disorder	Ketoprofen : Arthritis, musculoskeletal syndromes, dysmenorrhea – only adults (18 years old or older)
Articular gout	Allopurinol : Gouty arthritis, skin tophi, nephrolithiasis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Allopurinol : Gouty arthritis, skin tophi, nephrolithiasis – only adults (18 years old or older) Canacinumab : Gouty arthritis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Artificial respiration	Cisatracurium : Mechanical ventilation – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Rocuronium : Facilitation of tracheal intubation during rapid sequence induction, adjunct in the intensive care unit (ICU) – only adults (18 - 65 years old)
Arylsulfatase A deficiency	Atidarsagene autotemcel : Metachromatic leukodystrophy with reduced arylsulfatase A enzymatic activity – only infants (40 days - 1 year old) , children (1 year - 12 years old)
Ascariasis	Albendazole : Ascariasis, filariasis – only adolescents (12 years - 18 years old) , adults (18 - 65 years old) Mebendazole : Whipworm, pinworm, threadworm, roundworm, common hookworm, American hookworm – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Ascorbic acid deficiency	Vitamin C : Scurvy – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Vitamin C : Scurvy – only minors (0 - 18 years old) , adults (18 years old or older)
Aspiration of vomitus	Methylprednisolone : Pulmonary aspiration of gastric contents – only minors (0 - 18 years old) Methylprednisolone : Pulmonary aspiration of gastric contents – only adults (18 years old or older)
Aspiration pneumonitis	Dexamethasone : Aspiration pneumonitis – only adults (18 years old or older)
Aspiration pneumonitis due to and following anaesthesia during labour and delivery	Cimetidine : Risk of acid aspiration (Mendelson's Syndrome) before general anaesthesia – only adults (18 years old or older) Ranitidine : Prophylaxis of acid aspiration (Mendelson's) syndrome – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Assisted fertilization	Goserelin : Assisted reproduction – women, only adults (18 - 65 years old)
Asthmatic pulmonary eosinophilia	Benralizumab : Severe eosinophilic asthma – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Astrocytic tumor of brain	Carmustine : Glioblastoma, brain-stem gliomas, medulloblastoma, astrocytoma, ependymoma, brain metastases – only adults (18 years old or older)
Atonic epileptic seizure	Primidone : Grand mal and psychomotor (temporal lobe) epilepsy, focal or Jacksonian seizures, myoclonic jerks, akinetic attacks – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Atopic dermatitis	Abrocitinib : Moderate-to-severe atopic dermatitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Alclometasone : Eczema, primary irritant and allergic dermatitis – only adults (18 years old or older) Baricitinib : Moderate to severe atopic dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Betamethasone : Atopic dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Ciclosporin : Atopic dermatitis – only adults (18 years old or older) Clobetasone : Atopic dermatitis, irritant or allergic contact dermatitis, seborrhoeic dermatitis, nappy rash, photodermatitis – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Dexchlorpheniramine : Perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, angioedema Dupilumab : Moderate-to-severe atopic dermatitis – only adolescents (12 years - 18 years old) Dupilumab : Moderate-to-severe atopic dermatitis – only adults (18 years old or older) Ebastine : Allergic dermatitis – only adults (18 - 65 years old) Fluocinonide : Atopic eczema – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Lebrikizumab : Moderate-to-severe atopic dermatitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Mometasone : Atopic dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Pimecrolimus : Mild or moderate atopic dermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old) Tacrolimus : Severe atopic dermatitis – only children (1 year - 12 years old) Tacrolimus : Severe atopic dermatitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Tralokinumab : Moderate-to-severe atopic dermatitis – only adolescents (12 years - 18 years old) , adults (18 years old or older) Upadacitinib : Atopic dermatitis – only adolescents (12 years - 18 years old) , adults (18 years old or older)
Atopic neurodermatitis	Fluocinonide : Neurodermatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Hydrocortisone : Prurigo nodularis, neurodermatoses, otitis externa, intertrigo, napkin rash – only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Atrial fibrillation	Amiodarone : Tachyarrhythmias – only adults (18 years old or older) Oxprenolol : Supraventricular tachycardia, atrial fibrillation, ventricular tachycardia – only adults (18 years old or older) Vernakalant : Atrial fibrillation – only adults (18 - 65 years old)
Atrial flutter	Amiodarone : Tachyarrhythmias – only adults (18 years old or older)
Atrophic vulva	Prasterone : Vulvar and vaginal atrophy in postmenopausal women having moderate to severe symptoms – women, only adults (18 years old or older)
Attention deficit hyperactivity disorder	Atomoxetine : Attention-Deficit/Hyperactivity Disorder (ADHD) – only adults (18 years old or older) Atomoxetine : Attention-Deficit/Hyperactivity Disorder (ADHD) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Clonidine : Attention deficit hyperactivity disorder – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Guanfacine : Attention deficit hyperactivity disorder (ADHD) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Methylphenidate : Attention deficit hyperactivity disorder – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Atypical haemolytic uraemic syndrome	Eculizumab : Atypical haemolytic uremic syndrome (aHUS) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) Eculizumab : Atypical haemolytic uremic syndrome (aHUS) – only adults (18 years old or older) Ravulizumab : Atypical haemolytic uremic syndrome – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Autistic disorder	Chlorpromazine : Schizophrenia, autism – only children (1 year - 12 years old) , adolescents (12 years - 18 years old)
Autoimmune hemolytic anemia	Azathioprine : Auto-immune disorders – only adolescents (12 years - 18 years old) , adults (18 years old or older) Methylprednisolone : Autoimmune hemolytic anemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older) Prednisolone : Autoimmune hemolytic anemia – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Autoimmune hepatitis	Budesonide : Autoimmune hepatitis – only adults (18 years old or older) Prednisolone : Autoimmune hepatitis – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Autoimmune thrombocytopenia	Avatrombopag : Primary chronic immune thrombocytopenia (ITP) – only adults (18 - 65 years old) Immunoglobulins, normal human, IV : Primary immune thrombocytopenia (ITP) – only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Autosomal dominant polycystic kidney disease	Tolvaptan : Autosomal dominant polycystic kidney disease (ADPKD) – only adults (18 - 65 years old)
Axial spondyloarthritis	Adalimumab : Ankylosing spondylitis, axial spondyloarthritis, psoriatic arthritis – only adults (18 years old or older) Bimekizumab : Axial spondyloarthritis – only adults (18 years old or older) Certolizumab pegol : Axial spondyloarthritis – only adults (18 years old or older) Golimumab : Axial spondyloarthritis – only adults (18 years old or older) Upadacitinib : Axial spondyloarthritis – only adults (18 years old or older)
Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis	Etanercept : Non-radiographic axial spondyloarthritis – only adults (18 years old or older) Secukinumab : Non-radiographic axial spondyloarthritis (nr-axSpA) – only adults (18 years old or older)

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